优化二硫真菌毒性:烃链长度的调整

F. Baerlocher, M. Baerlocher, R. Langler, S. MacQuarrie, P. E. O'Connor
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引用次数: 13

摘要

以前鉴定的抗真菌类二硫化物是通过扩展烷基取代基来修饰的。虽然,主要的重点是磺砜二硫化物,硝基苯基烷基二硫化物和一对磺酯二硫化物也制备和测试。最佳的真菌毒性与具有7至10个碳原子的结构有关,其形式为无支链和/或苯环。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimizing disulfide fungitoxicity: Adjustment of hydrocarbon chain length
Previously identified classes of antifungal disulfides are modified by extending alkyl substituents. Although, the principal focus is on f -sulfone disulfides, one nitrophenyl alkyl disulfide and a pair of f -ester disulfides were also prepared and examined. Optimum fungitoxicity is associated with structures which have seven to ten carbon atoms in the form of unbranched chains and/or phenyl rings.
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