{"title":"氨甲环酸可预防血管紧张素转换酶抑制剂诱导的血管性水肿插管","authors":"Judge Ramzan, Kolaski Stephanie, Qadeer Farhan","doi":"10.23937/2474-3674/1510127","DOIUrl":null,"url":null,"abstract":"Angiotensin-converting enzyme inhibitors (ACE-I) are medications within the antihypertensive class that are used by nearly 108 million patients worldwide [1]. A rare but possibly life-threatening adverse effect of ACE-I is angioedema, which occurs due to elevated levels of bradykinin [2]. In this case report, we discuss a patient case where the use of tranexamic acid (TXA), an antifibrinolytic agent, prevented impending intubation due to ACE-I induced angioedema. CaSe RepoRt","PeriodicalId":13937,"journal":{"name":"International Journal of Critical Care and Emergency Medicine","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Use of Tranexamic Acid Prevents Intubation in ACE Inhibitor-Induced Angioedema\",\"authors\":\"Judge Ramzan, Kolaski Stephanie, Qadeer Farhan\",\"doi\":\"10.23937/2474-3674/1510127\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Angiotensin-converting enzyme inhibitors (ACE-I) are medications within the antihypertensive class that are used by nearly 108 million patients worldwide [1]. A rare but possibly life-threatening adverse effect of ACE-I is angioedema, which occurs due to elevated levels of bradykinin [2]. In this case report, we discuss a patient case where the use of tranexamic acid (TXA), an antifibrinolytic agent, prevented impending intubation due to ACE-I induced angioedema. CaSe RepoRt\",\"PeriodicalId\":13937,\"journal\":{\"name\":\"International Journal of Critical Care and Emergency Medicine\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Critical Care and Emergency Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23937/2474-3674/1510127\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Critical Care and Emergency Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2474-3674/1510127","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Use of Tranexamic Acid Prevents Intubation in ACE Inhibitor-Induced Angioedema
Angiotensin-converting enzyme inhibitors (ACE-I) are medications within the antihypertensive class that are used by nearly 108 million patients worldwide [1]. A rare but possibly life-threatening adverse effect of ACE-I is angioedema, which occurs due to elevated levels of bradykinin [2]. In this case report, we discuss a patient case where the use of tranexamic acid (TXA), an antifibrinolytic agent, prevented impending intubation due to ACE-I induced angioedema. CaSe RepoRt