棘皮草根提取物的定性和定性植物化学筛选

A. Sundari, R. Jayakumararaj
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引用次数: 0

摘要

植物化学物质作为治疗剂具有很大的功效。由于新发和再发传染病的发病率不断增加,因此迫切需要发现具有不同化学结构和新的作用机制的新治疗化合物。因此,本研究对棘草不同根提取物的植物成分进行了研究。按照标准程序对提取物进行定性和定量的植物化学分析。结果表明,在溶剂提取物中检测到类固醇的数量最多(分析的6种溶剂提取物中有5种),其次是生物碱(分析的4种溶剂提取物)。用于定性植物化学分析的六种溶剂均不含黄酮类、苷类、酚类、皂苷类和单宁类。棘皮根提取液中检出的化合物最多(5个),最少(1个)。定量分析结果表明,水提物中生物碱含量最高(4.54 mg/g),甲醇中黄酮类化合物含量最高(0.93 mg/g),苯酚含量最高(1.50 mg GAE/g),甲醇中单宁含量最高(0.84 mg TAE/g),甲醇中萜类化合物含量最高(3.66%)。该研究结果鼓励进一步的临床研究,以确定特定植物化学物质在体内的潜在有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
QUALITATIVE AND QUALITATIVE PHYTOCHEMICAL SCREENING OF ACANTHOSPERMUM HISPIDUM D.C. ROOT EXTRACTS
Phytochemicals have great potency as therapeutic agents. There is continuous and urgent need to discover newtherapeutic compounds with diverse chemical structures and novel mechanism of action because there has been analarming increase in the incidence of new and re-emerging infectious diseases. Hence, the present investigation wascarried out to assess the phytoconstituents of various root extracts of Acanthospermum hispidum. The extracts weresubjected to qualitative and quantitative phytochemical analyses as per standard procedures. The results showed thatsteroids were detected in maximum number of solvent extracts (five among six solvent extracts analysed) followed byalkaloids (in four solvent extracts). Flavonoids, glycosides, phenols, saponins and tannins were absent in all the sixsolvents used for qualitative phytochemical analyses. Maximum number (five) of compounds were identified in methanoland least (one) in hexane root extract of Acanthospermum. Findings of quantitative analyses highlighted that maximumcontent of alkaloids (4.54 mg/g) were determined in aqueous extract, flavonoids (0.93 mg/g) in methanol, phenols(1.50 mg GAE/g) in aqueous, tannins (0.84 mg TAE/g) in methanol and terpenoids (3.66 %) in methanol extracts. Theresult of this study is encouraging further clinical studies to determine the potential effectiveness of particularphytochemical in vivo.
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