Survey of vitamin D levels and hemoglobin among children in plateau area, Sichuan

Objective To investigate the correlation between vitamin D and anemia in preschool children in plateau area through the detection of vitamin D and hemoglobin levels in children aged 0–6 years in Daocheng county and Xiangcheng county, Ganzi prefecture, Sichuan province, and we provide scientific basis for the development of measures to prevent anemia in children. Methods Totally 2 122 children, aged 0-6 years were surveyed on the spot of Daocheng county and Xiangcheng county in altitude of 2 000- 0.05). Conclusion The vitamin D level of 2 122 children aged 0-6 years in Daocheng county and Xiangcheng County, Ganzi Prefecture, Sichuan Province, at an altitude of 2 000-4 000 meters, showed a decreasing trend with the increase of age, which was correlated with HGB level. Vitamin D deficiency may be related to the occurrence of anemia. 摘要：目的 对四川省甘孜州稻城县与乡城县0〜6岁儿童血清维生素D及血红蛋白水平的检测, 探讨高原地区0~6岁儿童维生素D与贫血的相关性, 为该地区制定预防儿童贫血措施提供科学依据。 方法 以分层整群随机抽样方法 选取四川省海拔高度在2 000~4 000 m的四川省甘孜州稻城县与乡城县, 选取稻城县与乡城县0~6岁儿童共2 122例, 进行现场问卷、体格检査, 采用高效液相色谱仪和全自动血常规分析仪, 检测血清25-羟维生素D(25-(OH)D)和血红 蛋白 (HGB)含量, 按25-(OH)D含量分为25-(OH)D缺乏组和充足组, 分析25-(OH)D与贫血的关系。 结果 2 122名 0~6岁儿童血清25-(OH)D和血液HGB平均水平分别为 (24.65±6.45) ng/mL和 (132.12±25.31) g/L, 25-(OH)D缺乏率 和贫血率分别为22.6%和22.2%。0~ 0.05)。 结论 海拔高度在 2 000~4 000 m的四川省甘孜州稻城县与乡城县0~6岁儿童25-(OH)D水平偏低, 25-(OH)D缺乏组的HGB水平低于 25-(OH)D充足组, 25-(OH)D缺乏可能是贫血的发生的主要原因。