局部抗真菌治疗联合指甲磨损治疗皮肤疣:单中心结果

K. Fukuyama
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引用次数: 0

摘要

本研究纳入了2017年4月至2020年3月期间就诊于关西Rosai医院皮肤科的4名女性,平均年龄73岁,诊断为皮肤疣,并接受手术清创和局部抗真菌药物治疗。患者有14个皮癣病变。在第一次就诊时进行手术撕脱。对14个钉子中的10个进行了评估。大约1年后,7个趾甲完全治愈,没有临床累及目标趾甲,氢氧化钾试验阴性。;三根指甲治疗失败(一根指甲受累率改善60%),一根指甲改善(30%或以上至小于60%)。所有10个可评估的皮癣病变在16个月内消失。本研究结果提示甲磨联合局部抗真菌药物治疗皮肤疣的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Topical antifungal therapy combined with nail abrasion for the treatment of dermatophytoma: single-center results
4 females, mean age 73 years) who visited the Department of Dermatology at Kansai Rosai Hospital between April 2017 and March 2020 diagnosed with dermatophytoma and treated by surgical debridement and topical antifungal drugs were included in this study. The patients had 14 dermatophytoma lesions. Surgical avulsion was performed at the first visit. Ten of the 14 nails were evaluated. By approximately 1 year, seven nails were completely cured with no clinical involvement of the target toenail as shown by the negative potassium hydroxide test. ; tTreatment failed for three nails (<30% improvement or worsening). The second efficacy evaluation was performed at the last visit or when changing therapeutic drugs were changed. This e second efficacy evaluation revealedshowed complete cure in eight nails, marked improvement (>60% improvement in nail involvement ratio) in one nail, and improvement( (30% or more to less than 60%) ) in one nail. All 10 evaluable dermatophytoma lesions disappeared in 16 months. The findings indicate the effectiveness of nail abrasion and topical antifungal drugs in treating dermatophytoma.
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