SARS-Cov-2感染(COVID-19)的主要诊断工具:当前的挑战

K. Kokilavani
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摘要

在不采取预防措施的情况下,大流行病的爆发一直是卫生保健管理部门控制死亡率的挑战。唯一的解决办法是通过大规模筛查和隔离感染者来控制传播。研究重点是开发低成本的快速诊断和筛查。世界各地正在使用和发展快速诊断方法。多项研究表明,RT-PCR、蛋白检测和CT应作为新冠肺炎患者常规检测的主要诊断手段。但这些诊断方法的快速性、敏感性和特异性三个因素仍不明确。因此,效率更高、时间要求更低的替代方法是切换超传播传染病检测的重要途径。现代,微流体技术也被称为芯片实验室或POCT,已广泛应用于癌症和病毒检测,特别是最近几天的病毒检测。POCT测试提供短时间结果的能力,适用于资源不足的诊所,甚至在家里。因此,我们看到了适用于COVID-19检测的小型化工具的重要性,它将承受目前昂贵的方法。尽管存在局限性,但经批准的检测方法在应对大流行方面仍然取得了良好的效果。我们回顾并强调,通过回顾广泛的研究背景,护理点测试(PCOT)方法并不比任何其他筛查方法少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary Diagnostic Tools for SARS-Cov-2 Infection (COVID-19): Current Challenge
Pandemic outbreaks are always a challenge for the health care management to hold the mortality rate when preventive measures are not established. The only solution is to control the spread by conducting massive screening and isolating affected ones from the healthy ones. The research concentration is to develop rapid diagnostics and screening at lower cost. Rapid diagnostic methods are being used and developed worldwide.Multiple studies suggest that RT-PCR, protein testing and CT should be the principal diagnostic instrument for routine testing in patients with COVID-19. But three factors are still indistinct in those diagnostic methods such as rapidity, sensitivity, and specificity. Thus, alternative approaches that provide higher efficiency and lower time requirement are highly appreciated for switching the super spread infectious disease detection.Moderntimes, microfluidics alternatively called lab on a chip or POCT have been widely used in cancer and viral detection, specifically for virus detection in very recent days. The ability of POCT tests to provide short time results,suitable in low resource clinics even at home. So, we saw the importance of miniaturized tools suitable for COVID-19 detection will endure the current expensive methods. Despite the limitations, approved tests are still experiencing good results against a great pandemic. We reviewed and highlighted the point of care testing (PCOT) method is not less than any other screening method by reviewing a wide research setting.
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