A. Razak, Maryam Said Mohamed Al Hajri, R. Shetty, K. Nayak
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引用次数: 4
摘要
房间隔缺损(Atrial septal defects, ASD)是一种已知的先天性心脏病。ASD导致右心容量超负荷增加。本研究的目的是评估经导管装置关闭的ASD患者左心室扭转变形。方法:所有经导管装置闭合伴第二开口ASD的成年患者均纳入研究。我们采用斑点跟踪超声心动图评估ASD患者第二口装置关闭前后左室扭转情况。结果:共纳入37例患者,其中女性22例,男性15例。平均年龄28±19岁。经导管关闭后左室基底旋转峰明显改善(P = 0.028)。经导管闭合后左室扭转(闭合前为2.88±0.99˚/cm,闭合后为3.40±1.41˚/cm, P = 0.009)和扭转(闭合前为15.12±4.69˚,闭合后为17.95±6.21˚,P = 0.005)差异均有统计学意义。包括舒张末期容积和收缩期容积在内的容积评估在装置关闭后均有显著改善(P = 0.02, P < 0.01)。结论:左室扭转和扭转峰值的增加主要是由于ASD装置关闭后收缩顺时针旋转峰值的提高。年轻时左室扭转在ASD闭合后得到改善。
Left Ventricular Torsion Deformation in Atrial Septal Defect Patients Undergoing Transcatheter Device Closure
Introduction: Atrial septal defects (ASD) considered being one of the known congenital heart diseases. ASD causes increased volume overload of the right heart. The purpose of this study was to evaluate left ventricular (LV) torsion deformation in ASD patients undergoing transcatheter device closure. Methods: All adult patients who underwent transcatheter device closure with ostium secundum ASD were included in the study. We assessed LV torsion in ostium secundum ASD patient’s pre and post device closure by using speckle tracking echocardiography. Results: A total of 37 patients (22 females and 15 males) were included in this study. The average age was 28 ± 19 years. LV peak basal rotation improved significantly (P = 0.028) in post transcatheter closure. LV torsion (2.88 ± 0.99˚/cm before vs. 3.40 ± 1.41˚/cm after closure, P = 0.009) and twisting (15.12 ± 4.69˚ before vs. 17.95 ± 6.21˚ after closure, P = 0.005) were statistically significant in post transcatheter closure. Volumetric assessment of LV including end-diastolic volume and systolic volume showed significant improvement (P = 0.02, P < 0.01) post device closure. Conclusions: The increased peak LV twisting and torsion was mainly attributed to the improved peak systolic clockwise rotation after ASD device closure. The LV twisting at a younger age was improved after the closure of ASD.