B. Lattuca, F. Leclercq, J. Macia, R. Gervasoni, T. Cung, J. Pasquié, F. Massin, S. Cade, F. Cransac, Mariama Akodad, F. Roubille
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Colchicine: A Promising Drug in Clinical Translation, A Minireview Focused on Cardiovascular Diseases
Colchicine is a venerable drug used for centuries for rheumatic diseases with potential pleiotropic anti-inflammatory effects. One of the main concerns remains the tolerability especially digestive side effects, but this aspect has been improved by many pharmacological improvements. Nowadays, colchine is a promising drug for cancer therapy and cardiovascular diseases with several studies currently going on, an improved therapeutic window and a wider range of translations in cardioprotection but also in atrial fibrillation, ischemic cardiopathy or pericarditis.
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