Krishna Kumar, H. Gopalan, Jayalakshmi Jayaprakash
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引用次数: 0
摘要
背景。原发性脑出血是一种高发病率和死亡率的神经系统疾病。在这种情况下,结果预测对于合理分配可用资源是必要的。我们的研究旨在根据入院时脑部CT平片研究确定住院死亡率的放射学预测因素,并在此基础上开发预后评分系统。材料和方法。我们收集了182例原发性自发性脑出血患者的临床和放射学资料。采用未经调整的逻辑回归对住院死亡率的放射学预测因子进行双变量分析。将发现有显著性的变量放入多元逻辑回归模型中。多元逻辑回归的结果被作为开发评分系统的基础。结果。在我们的研究中,死亡率为23.6% (N = 43)。经过多因素分析,中线移位(MLS)、是否存在脑室内出血(IVH)、脑出血体积和血肿位置是死亡率的重要预测因素。基于确定的放射学变量,建立了一个五分制的预后评分系统(AUROC = 0.925, 95% CI 0.887-0.964),评分越高,死亡率越高。已建立的评分系统MIVL可以帮助医生更好地对患者进行预后咨询。
Formulation of a radiological scoring system to prognosticate patients with primary intracerebral haemorrhage
Background. Primary intracerebral haemorrhage is a neurological condition associated with high morbidity and mortality. Outcome prediction is necessary to allocate the available resources in such cases judicially. Our study aims to identify the radiological predictors of in-hospital mortality based on a plain CT study of the brain at admission and to develop a prognostic scoring system based on them.
Material and methods. We collected the clinical and radiological data from 182 consecutive patients who presented with primary spontaneous ICH. Bivariate analysis of radiological predictors of in-hospital mortality was undertaken using unadjusted logistic regression. Those variables found to have significance were put into a multivariate logistic regression model. The Results of multivariate logistic regression were treated as a foundation for developing the scoring system.
Results. The mortality rate in our series was 23.6% (N = 43). After multivariate analysis, Midline shift (MLS), presence or absence of intraventricular haemorrhage (IVH), Volume of ICH and Location of haematoma were significant predictors of mortality. Based on the identified radiological variables, a five-score prognostic scoring system (AUROC = 0.925, 95% CI 0.887–0.964)) was developed, with higher scores indicating higher mortality.
Conclusions. The established scoring system, MIVL, may help physicians to do better patient counselling regarding outcomes.