动脉性高血压未控制患者急诊救治的有效性和安全性评价

Q4 Medicine

Sklifosovsky Journal Emergency Medical Care Pub Date : 2022-12-11 DOI:10.24884/2072-6716-2022-23-4-41-47

V. V. Ruksin, O. V. Grishin, V. Kitsyshin, I. Lukyanova

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引用次数: 0

摘要

对91例动脉性高血压未得到控制的患者进行联合降压药的疗效和安全性比较。30例患者接受卡托普利联合呋塞米;32 -莫onidine和呋塞米;莫onidine和硝苯地平。药物的处方采用固定随机化，使用随机数字表。结果表明卡托普利与呋塞米联用降压效果充分但不稳定，莫onidine与硝苯地平联用降压效果充分但不稳定，莫onidine与呋塞米联用降压效果充分且稳定。当使用莫onidine和硝苯地平时，检测到血压过度降低的频率明显更高。提出的血压监测资金登记和评估方法在院前阶段容易实现。

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Evaluation of the efficiency and safety of emergency medical care with uncontrolled arterial hypertension

In 91 patients with uncontrolled arterial hypertension, the efficacy and safety of combinations of antihypertensive drugs were compared. 30 patients received a combination of captopril and furosemide; 32 — moxonidine and furosemide; 29 — moxonidine and nifedipine. Drugs were prescribed by fixed randomization using a table of random numbers. It is shown that the combination of captopril and furosemide has a sufficient, but not stable antihypertensive effect, moxonidine and nifedipine, moxonidine and furosemide — a sufficient and stable effect. When using moxonidine and nifedipine, a significantly higher frequency of excessive lowering of blood pressure was detected. The proposed method of registration and evaluation of blood pressure monitoring of funds is easily feasible at the pre-hospital stage.

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来源期刊

Sklifosovsky Journal Emergency Medical Care Medicine-Emergency Medicine

CiteScore

0.90

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal "Neotlozhnaia meditsinskaia pomoshch" (parallel titles: Zhurnal im. N.V. Sklifosovskogo "Neotlozhnai︠a︡ medit︠s︡inskai︠a︡ pomoshch", "Sklifosovsky Journal of Emergency Medical Care") seeks to publish original research articles, literature reviews, case reports, brief reports on clinical practice, and other suitable material submitted by professionals involved in the diagnosis and treatment of acute medical and surgical conditions.