{"title":"糖尿病迷你猪血糖开关杂交控制Göttingen","authors":"K. Lunze, B. Misgeld, S. Leonhardt","doi":"10.3182/20140824-6-ZA-1003.02156","DOIUrl":null,"url":null,"abstract":"Abstract This paper presents the results of our recent blood glucose control trials with diabetic Gottingen minipigs. In particular, we describe our new switching hybrid control algorithm which uses different sampling intervals and insulin application strategies for daytime and night phases. The experimental results of the control application to two animals are given and compared with manual insulin treatment. Both strategies for glucose regulation result in comparable blood glucose trajectories even though meals were not announced to the controller but were taken into account in the manual protocol.","PeriodicalId":13260,"journal":{"name":"IFAC Proceedings Volumes","volume":"9 1","pages":"10156-10161"},"PeriodicalIF":0.0000,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Switching Hybrid Control of Blood Glucose in Diabetic Göttingen Minipigs\",\"authors\":\"K. Lunze, B. Misgeld, S. Leonhardt\",\"doi\":\"10.3182/20140824-6-ZA-1003.02156\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract This paper presents the results of our recent blood glucose control trials with diabetic Gottingen minipigs. In particular, we describe our new switching hybrid control algorithm which uses different sampling intervals and insulin application strategies for daytime and night phases. The experimental results of the control application to two animals are given and compared with manual insulin treatment. Both strategies for glucose regulation result in comparable blood glucose trajectories even though meals were not announced to the controller but were taken into account in the manual protocol.\",\"PeriodicalId\":13260,\"journal\":{\"name\":\"IFAC Proceedings Volumes\",\"volume\":\"9 1\",\"pages\":\"10156-10161\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IFAC Proceedings Volumes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3182/20140824-6-ZA-1003.02156\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IFAC Proceedings Volumes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3182/20140824-6-ZA-1003.02156","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Switching Hybrid Control of Blood Glucose in Diabetic Göttingen Minipigs
Abstract This paper presents the results of our recent blood glucose control trials with diabetic Gottingen minipigs. In particular, we describe our new switching hybrid control algorithm which uses different sampling intervals and insulin application strategies for daytime and night phases. The experimental results of the control application to two animals are given and compared with manual insulin treatment. Both strategies for glucose regulation result in comparable blood glucose trajectories even though meals were not announced to the controller but were taken into account in the manual protocol.