扁平苔藓患者心房机电耦合受损

European Journal of Echocardiography Pub Date : 2021-02-08 DOI:10.1093/EHJCI/JEAA356.109

I. Jafaripour, Z. Aryanian, S. Hosseinzadeh, R. Pourkia, MM Ansari Ramandi, A Kebria Shirzadian, S. Tabari, M. Pourkia

{"title":"扁平苔藓患者心房机电耦合受损","authors":"I. Jafaripour, Z. Aryanian, S. Hosseinzadeh, R. Pourkia, MM Ansari Ramandi, A Kebria Shirzadian, S. Tabari, M. Pourkia","doi":"10.1093/EHJCI/JEAA356.109","DOIUrl":null,"url":null,"abstract":"\n \n \n Type of funding sources: None.\n \n \n \n Lichen planus (LP) which is a chronic inflammatory disease can cause impaired atrial electromechanical coupling, leading to increased risk of atrial fibrillation.\n \n \n \n The present study aimed to evaluate atrial electromechanical coupling in LP patients by using electrocardiography (ECG) and echocardiography.\n \n \n \n Forty-six LP patients were investigated in this cross-sectional case-control study. The control group comprised healthy individuals selected in age and gender-matched manner. Echocardiography and ECG were done for all patients to show inter and intra-atrial electromechanical delays and P wave dispersion respectively. The electromechanical delays were calculated by using the difference between the delays from the onset of the P wave on ECG to the onset of A wave on tissue Doppler recordings of the different areas.\n \n \n \n The baseline characteristics of the case and control group were similar and did not differ significantly. The P wave dispersion was 45.63 ± 3.48 milliseconds in the LP group in comparison to 36.56 ± 2.87 milliseconds in the control group (p < 0.001). As shown in the table, the intra and inter-atrial electromechanical delays were also significantly prolonged in LP patients when compared to the control group (p < 0.001). There was no significant difference between the left and right ventricular systolic function and diastolic function of the two groups.\n \n \n \n The results of the study indicate the presence of significant impaired atrial electromechanical coupling in patients with LP confirmed by both electrocardiographic and echocardiographic tools.\n Electromechanical delays Case N = 46 (mean ± SD) Control N = 46 (mean ± SD) P value Septal - PA (msec) 59.71 ± 13.24 44.39 ± 11.07 0.002 Lateral - PA (msec) 55.71 ± 13.26 48.89 ± 11.21 0.009 Tricuspid - PA (msec) 52.37 ± 13.12 43.28 ± 10.58 0.002 Inter-atrial delay (msec) (lateral PA−RV PA) 8.47 ± 1.62 6.37 ± 1.36 <0.001 Intra-atrial delay (msec) (LA) [lateral PA−septal PA] 4.80 ± 1.48 3.83 ± 0.82 <0.001 Intra-atrial delay (msec) (RA) [septal PA−RV PA] 3.91 ± 0.96 2.02 ± 0.71 <0.001 PA Delay from the onset of the P wave on ECG to the onset of A wave on tissue Doppler, N: number, SD: Standard Deviation, LA: Left Atrium, RA: Right Atrium, RV: Right Ventricle\n","PeriodicalId":11963,"journal":{"name":"European Journal of Echocardiography","volume":"19 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impaired atrial electromechanical coupling in lichen planus patients\",\"authors\":\"I. Jafaripour, Z. Aryanian, S. Hosseinzadeh, R. Pourkia, MM Ansari Ramandi, A Kebria Shirzadian, S. Tabari, M. Pourkia\",\"doi\":\"10.1093/EHJCI/JEAA356.109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n \\n Type of funding sources: None.\\n \\n \\n \\n Lichen planus (LP) which is a chronic inflammatory disease can cause impaired atrial electromechanical coupling, leading to increased risk of atrial fibrillation.\\n \\n \\n \\n The present study aimed to evaluate atrial electromechanical coupling in LP patients by using electrocardiography (ECG) and echocardiography.\\n \\n \\n \\n Forty-six LP patients were investigated in this cross-sectional case-control study. The control group comprised healthy individuals selected in age and gender-matched manner. Echocardiography and ECG were done for all patients to show inter and intra-atrial electromechanical delays and P wave dispersion respectively. The electromechanical delays were calculated by using the difference between the delays from the onset of the P wave on ECG to the onset of A wave on tissue Doppler recordings of the different areas.\\n \\n \\n \\n The baseline characteristics of the case and control group were similar and did not differ significantly. The P wave dispersion was 45.63 ± 3.48 milliseconds in the LP group in comparison to 36.56 ± 2.87 milliseconds in the control group (p < 0.001). As shown in the table, the intra and inter-atrial electromechanical delays were also significantly prolonged in LP patients when compared to the control group (p < 0.001). There was no significant difference between the left and right ventricular systolic function and diastolic function of the two groups.\\n \\n \\n \\n The results of the study indicate the presence of significant impaired atrial electromechanical coupling in patients with LP confirmed by both electrocardiographic and echocardiographic tools.\\n Electromechanical delays Case N = 46 (mean ± SD) Control N = 46 (mean ± SD) P value Septal - PA (msec) 59.71 ± 13.24 44.39 ± 11.07 0.002 Lateral - PA (msec) 55.71 ± 13.26 48.89 ± 11.21 0.009 Tricuspid - PA (msec) 52.37 ± 13.12 43.28 ± 10.58 0.002 Inter-atrial delay (msec) (lateral PA−RV PA) 8.47 ± 1.62 6.37 ± 1.36 <0.001 Intra-atrial delay (msec) (LA) [lateral PA−septal PA] 4.80 ± 1.48 3.83 ± 0.82 <0.001 Intra-atrial delay (msec) (RA) [septal PA−RV PA] 3.91 ± 0.96 2.02 ± 0.71 <0.001 PA Delay from the onset of the P wave on ECG to the onset of A wave on tissue Doppler, N: number, SD: Standard Deviation, LA: Left Atrium, RA: Right Atrium, RV: Right Ventricle\\n\",\"PeriodicalId\":11963,\"journal\":{\"name\":\"European Journal of Echocardiography\",\"volume\":\"19 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Echocardiography\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/EHJCI/JEAA356.109\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Echocardiography","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/EHJCI/JEAA356.109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

资金来源类型:无。扁平苔藓(LP)是一种慢性炎症性疾病，可导致心房机电耦合受损，导致房颤的风险增加。本研究旨在应用心电图和超声心动图评价LP患者的心房机电耦合。在这项横断面病例对照研究中，对46例LP患者进行了调查。对照组由年龄和性别匹配的健康个体组成。所有患者均行超声心动图和心电图检查，分别显示心房间和心房内机电延迟和P波弥散。利用不同区域组织多普勒记录的P波开始与A波开始的延迟之差来计算机电延迟。病例和对照组的基线特征相似，无显著差异。LP组P波弥散时间为45.63±3.48毫秒，对照组为36.56±2.87毫秒(P < 0.001)。如表所示，与对照组相比，LP患者房内和房间机电延迟也显著延长(p < 0.001)。两组患者左右心室收缩功能和舒张功能差异无统计学意义。研究结果表明，经心电图和超声心动图证实，LP患者存在明显的心房机电耦合受损。机电延误情况下N = 46(平均数±标准差)控制N = 46(平均数±标准差)P值间隔- PA(微秒)59.71±13.24 44.39±11.07 - 0.002横向- PA(微秒)55.71±13.26 48.89±11.21 - 0.009三尖瓣- PA(微秒)52.37±13.12 - 43.28±10.58 - 0.002 Inter-atrial延迟(毫秒)(横向PA−RV PA) 8.47±1.62 - 6.37±1.36 < 0.001心房内延迟(毫秒)(拉)(横向PA−间隔PA) 4.80±1.48 - 3.83±0.82 < 0.001心房内延迟(毫秒)(RA)(隔PA−RV PA) 3.91±0.96 - 2.02±0.71 < 0.001 PA延迟从心电图P波开始到组织多普勒A波开始，N:数，SD:标准差，LA:左心房，RA:右心房，RV:右心室

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Impaired atrial electromechanical coupling in lichen planus patients

Type of funding sources: None. Lichen planus (LP) which is a chronic inflammatory disease can cause impaired atrial electromechanical coupling, leading to increased risk of atrial fibrillation. The present study aimed to evaluate atrial electromechanical coupling in LP patients by using electrocardiography (ECG) and echocardiography. Forty-six LP patients were investigated in this cross-sectional case-control study. The control group comprised healthy individuals selected in age and gender-matched manner. Echocardiography and ECG were done for all patients to show inter and intra-atrial electromechanical delays and P wave dispersion respectively. The electromechanical delays were calculated by using the difference between the delays from the onset of the P wave on ECG to the onset of A wave on tissue Doppler recordings of the different areas. The baseline characteristics of the case and control group were similar and did not differ significantly. The P wave dispersion was 45.63 ± 3.48 milliseconds in the LP group in comparison to 36.56 ± 2.87 milliseconds in the control group (p < 0.001). As shown in the table, the intra and inter-atrial electromechanical delays were also significantly prolonged in LP patients when compared to the control group (p < 0.001). There was no significant difference between the left and right ventricular systolic function and diastolic function of the two groups. The results of the study indicate the presence of significant impaired atrial electromechanical coupling in patients with LP confirmed by both electrocardiographic and echocardiographic tools. Electromechanical delays Case N = 46 (mean ± SD) Control N = 46 (mean ± SD) P value Septal - PA (msec) 59.71 ± 13.24 44.39 ± 11.07 0.002 Lateral - PA (msec) 55.71 ± 13.26 48.89 ± 11.21 0.009 Tricuspid - PA (msec) 52.37 ± 13.12 43.28 ± 10.58 0.002 Inter-atrial delay (msec) (lateral PA−RV PA) 8.47 ± 1.62 6.37 ± 1.36 <0.001 Intra-atrial delay (msec) (LA) [lateral PA−septal PA] 4.80 ± 1.48 3.83 ± 0.82 <0.001 Intra-atrial delay (msec) (RA) [septal PA−RV PA] 3.91 ± 0.96 2.02 ± 0.71 <0.001 PA Delay from the onset of the P wave on ECG to the onset of A wave on tissue Doppler, N: number, SD: Standard Deviation, LA: Left Atrium, RA: Right Atrium, RV: Right Ventricle

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

European Journal of Echocardiography 医学-心血管系统

自引率

0.00%

发文量

审稿时长

>12 weeks