{"title":"过敏原的常见结构","authors":"A. Pomés","doi":"10.1016/j.allerg.2008.01.013","DOIUrl":null,"url":null,"abstract":"<div><p>Allergens can be classified into different families of proteins with common structural features, but there are not structures and functions in common to all allergens. High degree of amino acid sequence identity between homologous proteins reflects on common molecular surface patches that are the basis of allergenic cross-reactivity. Allergens need to be available for exposure (dose) to individuals susceptible (genetic predisposition) to develop allergies.</p></div>","PeriodicalId":92953,"journal":{"name":"Revue francaise d'allergologie et d'immunologie clinique","volume":"48 3","pages":"Pages 139-142"},"PeriodicalIF":0.0000,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.allerg.2008.01.013","citationCount":"4","resultStr":"{\"title\":\"Common structures of allergens\",\"authors\":\"A. Pomés\",\"doi\":\"10.1016/j.allerg.2008.01.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Allergens can be classified into different families of proteins with common structural features, but there are not structures and functions in common to all allergens. High degree of amino acid sequence identity between homologous proteins reflects on common molecular surface patches that are the basis of allergenic cross-reactivity. Allergens need to be available for exposure (dose) to individuals susceptible (genetic predisposition) to develop allergies.</p></div>\",\"PeriodicalId\":92953,\"journal\":{\"name\":\"Revue francaise d'allergologie et d'immunologie clinique\",\"volume\":\"48 3\",\"pages\":\"Pages 139-142\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.allerg.2008.01.013\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue francaise d'allergologie et d'immunologie clinique\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0335745708000385\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue francaise d'allergologie et d'immunologie clinique","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0335745708000385","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Allergens can be classified into different families of proteins with common structural features, but there are not structures and functions in common to all allergens. High degree of amino acid sequence identity between homologous proteins reflects on common molecular surface patches that are the basis of allergenic cross-reactivity. Allergens need to be available for exposure (dose) to individuals susceptible (genetic predisposition) to develop allergies.
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