非p450酶诱导抗癫痫药物是胶质母细胞瘤患者ADEs的最佳选择吗?

Molecular & Cellular Epilepsy Pub Date : 2014-02-15 DOI:10.14800/MCE.32

Mao Qing

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引用次数: 0

摘要

一些临床研究对胶质瘤切除术后使用P450酶诱导和非酶诱导抗癫痫药物预防癫痫发作的预后进行了研究。然而，这些研究的结果并不一致。需要更多的多中心随机对照试验来提供aed在治疗胶质瘤相关癫痫发作中的作用的一级证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Is non-P450 enzyme inducing antiepileptic drugs the best ADEs choice for glioblastoma patients?

The seizure prognosis of using P450 enzyme inducing and non-enzyme inducing antiepileptic drugs for seizure prophylaxis after glioma resection surgery has been investigated in several clinical studies. However, the results of these studies are inconsistent. Additional multicenter RCTs are necessary to provide class I evidence on the role of AEDs in the treatment of glioma associated seizure.

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Molecular & Cellular Epilepsy

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