Effects of Plasma transfusion on various hematological and biochemical parameters in goats

This study investigated the clinical and hematological responses of plasma transfusion and hematinic administration in severely anemic goats. The blood profile of the recipient goats were assessed for hematological: Total Erythrocyte Count (TEC), Total Leukocyte Count (TLC), Hemoglobin (Hb), Packed Cell Volume (PCV), Neutrophil, Eosinophil, Lymphocyte, Monocyte, and Electrolytes and Biochemical parameters: Alanine Transaminase (ALT), Aspartate Transaminase (AST), Creatinine and Total Protein (TP) before and after (1st, 7th, 14th, 21th, 28th days) treatment with plasma transfusion or hematinic administration. In plasma transfusion group (Group A), TEC, PCV, Hb, ALT, AST and TP were increased significantly (p < 0.01) at 1st, 7th, 14th, 21th, 28th days of post-transfusion in comparison to pre-transfusion values. In the hematinic group (Group B), two patients died treated with hematinic. However, no significant changes (p > 0.05) in clinical parameters, electrolytes (K+, Na+ and Cl−) levels and creatinine values were observed in recipient goats after plasma transfusion and hematinic administration. After 28 days of treatment, all patients of plasma transfusion group (100%) and three in hematinic treatment group (60%) were recovered successfully. The plasma transfusion was found superior to hematinic administration to upgrade the hematological and biochemical parameters in anemic goats. It did not produce any adverse reaction in the recipient goats. Plasma transfusion could be an effective tool for the clinical management of anemic goats.