{"title":"大鼠皮肤“基质”的糖胺聚糖。","authors":"J. M. Mathieson, R. H. Pearce","doi":"10.1139/O63-261","DOIUrl":null,"url":null,"abstract":"The glycosaminoglycan was isolated from an isotonic saline extract of dry, fat-free rat skin in better than 80% yield. The product was virtually homogeneous as judged by electrophoresis on paper at several pH values, by electrophoresis on sponge rubber, and by fractional precipitation of the calcium and sodium salts with ethanol. The material corresponded to hyaluronate in electrophoretic mobility, solubility of its salts in ethanol, and in its content of a single hexosamine, glucosamine.","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"109 1","pages":"2327-35"},"PeriodicalIF":0.0000,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"THE GLYCOSAMINOGLYCAN OF THE 'GROUND SUBSTANCE' OF RAT SKIN.\",\"authors\":\"J. M. Mathieson, R. H. Pearce\",\"doi\":\"10.1139/O63-261\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The glycosaminoglycan was isolated from an isotonic saline extract of dry, fat-free rat skin in better than 80% yield. The product was virtually homogeneous as judged by electrophoresis on paper at several pH values, by electrophoresis on sponge rubber, and by fractional precipitation of the calcium and sodium salts with ethanol. The material corresponded to hyaluronate in electrophoretic mobility, solubility of its salts in ethanol, and in its content of a single hexosamine, glucosamine.\",\"PeriodicalId\":9531,\"journal\":{\"name\":\"Canadian journal of biochemistry and physiology\",\"volume\":\"109 1\",\"pages\":\"2327-35\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1963-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian journal of biochemistry and physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1139/O63-261\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian journal of biochemistry and physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1139/O63-261","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
THE GLYCOSAMINOGLYCAN OF THE 'GROUND SUBSTANCE' OF RAT SKIN.
The glycosaminoglycan was isolated from an isotonic saline extract of dry, fat-free rat skin in better than 80% yield. The product was virtually homogeneous as judged by electrophoresis on paper at several pH values, by electrophoresis on sponge rubber, and by fractional precipitation of the calcium and sodium salts with ethanol. The material corresponded to hyaluronate in electrophoretic mobility, solubility of its salts in ethanol, and in its content of a single hexosamine, glucosamine.
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