Wei-Yi Ding, Jun Ai, Xin-Long Wang, Fayang G. Qiu, Qing Lv, Ping Fang, Fan-Fan Hou, Yong-Ming Yan, Yong-Xian Cheng
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ChemInform Abstract: Isolation of Lingzhifuran A and Lingzhilactones D—F from Ganoderma lucidum as Specific Smad3 Phosphorylation Inhibitors and Total Synthesis of Lingzhifuran A.
The four new phenolic meroterpenoids, lingzhifuran A (I) and lingzhilactones D—F (II—IV), show inhibitory activities against transforming growth factor-β1-induced Smad3 phosphorylation.
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