信任，炎症生物标志物和逆境:一项新的研究和临床意义

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-03-01 DOI:10.1080/03069885.2022.2039899

Z. Chouliara, Peter G. Barlow

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引用次数: 0

摘要

逆境和创伤的幸存者会经历高度的痛苦、人际挑战和身体健康状况不佳。我们研究了信任在创伤相关心理和生理反应中的作用。测量了苏格兰25名参与者的血清c反应蛋白、皮质醇、肿瘤坏死因子- α和白细胞介素-8的浓度。使用童年创伤问卷和生活事件检查表评估创伤史和经历。创伤症状以事件影响量表(Impact of Event Scale)测量。人际信任采用信任量表进行测量。创伤史和炎症生物标志物浓度是创伤症状学的重要预测因子，信任是一个协变量。创伤后的心理和生理反应似乎密切相关。信任可以调节逆境中的痛苦和生理。

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Trust, inflammatory biomarkers and adversity: a novel investigation and clinical implications

ABSTRACT Survivors of adversity and trauma experience high levels of distress, interpersonal challenges and poor physical health. We investigated the role of trust in trauma-related psychological and physiological responses. Serum concentrations of C-reactive protein, cortisol, tumour necrosis factor-alpha and interleukin-8 from 25 participants in Scotland were measured. Trauma history and experience were assessed using the Childhood Trauma Questionnaire and Life Events Checklist. Trauma symptomatology was measured by the Impact of Event Scale. Interpersonal trust was measured using the Trust Scale. Trauma history and inflammatory biomarker concentrations were significant predictors of trauma symptomatology with trust as a covariate. Psychological and physiological responses after trauma seem strongly linked. Trust can mediate distress and physiology in adversity.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.