心血管支架制造技术及材料综述

IF 2.8 3区工程技术 Q2 ENGINEERING, MANUFACTURING

Advances in Production Engineering & Management Pub Date : 2020-12-24 DOI:10.14743/apem2020.4.373

B. Polanec, J. Kramberger, S. Glodež

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引用次数: 10

摘要

本文的目的是对支架的生产技术进行概述，并考虑其设计和材料。自从在动脉粥样硬化治疗中开始使用支架以来，其发展发生了迅速变化。随着材料科学、处理技术和新的制造工艺的发展，各种支架也被开发出来。以这种方式，发展已经从最初的裸金属支架(BMS)转变为药物洗脱支架(DES)和生物可吸收支架(BRS)，它们由可生物降解的聚合物或金属制成。各种研究一致认为，有必要通过分析和数值研究来进一步审查实验获得的材料特性。在这里，计算建模(有限元分析- FEA和计算流体动力学- CFD)被认为是评估支架力学和优化支架设计的有价值的工具。近年来，支架制造技术的发展也发生了变化和补充。如今，3D打印可能是一种令人兴奋的制造方法，可以生产高分子生物材料，适用于最新一代的生物可降解支架应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A review of production technologies and materials for manufacturing of cardiovascular stents

The purpose of this article is to give a general overview of the production technologies of stents with consideration of their design and materials. Since the beginning of the use of stents in medicine for atherosclerosis treatment, their development has changed rapidly. Various stents have also been developed with the development of materials science, treatment techniques and new manufacturing processes. In this way the development has shifted from the initial bare-metal stents (BMS), to drug-eluting stents (DES) and bio-resorbable stents (BRS), which are made of biodegradable polymers or metals. Various studies agree that it will be necessary to further review the experimentally obtained material properties with analytical and numerical studies. Here, the computational modelling (Finite element analysis - FEA and Computational fluid dynamics - CFD) was found as a valuable tool when evaluating stent mechanics and optimizing stent design. The development of the stent manufacturing technologies has also changed and been supplemented over the years. Nowadays, 3D printing could be an exciting manufacturing method to produce polymeric bio-materials, suitable for the latest generation of bio-degradable stents applications.

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来源期刊

Advances in Production Engineering & Management ENGINEERING, MANUFACTURINGMATERIALS SCIENC-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

5.90

自引率

22.20%

发文量

期刊介绍： Advances in Production Engineering & Management (APEM journal) is an interdisciplinary international academic journal published quarterly. The main goal of the APEM journal is to present original, high quality, theoretical and application-oriented research developments in all areas of production engineering and production management to a broad audience of academics and practitioners. In order to bridge the gap between theory and practice, applications based on advanced theory and case studies are particularly welcome. For theoretical papers, their originality and research contributions are the main factors in the evaluation process. General approaches, formalisms, algorithms or techniques should be illustrated with significant applications that demonstrate their applicability to real-world problems. Please note the APEM journal is not intended especially for studying problems in the finance, economics, business, and bank sectors even though the methodology in the paper is quality/project management oriented. Therefore, the papers should include a substantial level of engineering issues in the field of manufacturing engineering.