求解Michaelis-Menten非线性生化反应模型的Kashuri Fundo分解法

IF 2.9 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
H. Peker, Fatma Aybike Çuha, Bilge Peker
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引用次数: 0

摘要

在现实生活中的大多数问题中,我们都会遇到非线性微分方程。用这些方程来模拟问题,问题就容易理解了。这样,就更容易解释问题并得出结果。1913年Michaelis和Menten提出的描述酶过程的基本酶反应模型就是一个非线性微分方程的例子。该模型是用于模拟酶催化反应的机制中最简单和最著名的方法之一,也是研究最多的。对于大多数非线性微分方程,很难得到解析解。由于这个原因,人们进行了各种各样的研究来寻找这类方程的近似解。在这些研究中,混合使用两种不同方法的研究引起了人们的注意。本研究采用Kashuri Fundo变换法和Adomian分解法的混合形式,即所谓的Kashuri Fundo分解法,以这种方式求解Michaelis-Menten非线性生化反应模型。将该方法应用于生化反应模型,无需复杂的计算即可得到该模型的近似解。结果表明,该方法是求解非线性微分方程的一种有效、可靠、简便、省时的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Kashuri Fundo Decomposition Method for Solving Michaelis-Menten Nonlinear Biochemical Reaction Model
In most of the real life problems, we encounter with nonlinear differential equations. Problems are made more understandable by modeling them with these equations. In this way, it becomes easier to interpret the problems and reach the results. In 1913, the basic enzymatic reaction model introduced by Michaelis and Menten to describe enzyme processes is an example of nonlinear differential equation. This model is the one of the simplest and best-known approaches of the mechanisms used to model enzyme-catalyzed reactions and is the most studied. For most nonlinear differential equations, it is very difficult to get an analytical solution. For this reason, various studies have been carried out to find approximate solutions to such equations. Among these studies, those in which two different methods are used by blending attract attention. In this study, a blended form of the Kashuri Fundo transform method and the Adomian decomposition method, so-called the Kashuri Fundo decomposition method, is used to find a solution to the Michaelis-Menten nonlinear biochemical reaction model in this way. This method has been applied to the biochemical reaction model and an approximate solution has been obtained for this model without complex calculations. This shows that the hybrid method is an effective, reliable, simpler and time-saving method in reaching the solutions of nonlinear differential equations.
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来源期刊
CiteScore
4.40
自引率
26.90%
发文量
71
审稿时长
2 months
期刊介绍: MATCH Communications in Mathematical and in Computer Chemistry publishes papers of original research as well as reviews on chemically important mathematical results and non-routine applications of mathematical techniques to chemical problems. A paper acceptable for publication must contain non-trivial mathematics or communicate non-routine computer-based procedures AND have a clear connection to chemistry. Papers are published without any processing or publication charge.
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