骨髓增生异常综合征细胞遗传学的临床意义

IF 1 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Labmedicine Pub Date : 2015-09-23 DOI:10.1309/EWKEBC48R8KYETR3

A. Haddad, J. Maciejewski, M. Kalaycio

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引用次数: 1

摘要

骨髓增生异常综合征(mds)是一组异质性疾病，其特征是由于造血干细胞功能失调导致的造血功能不全与细胞减少相关。骨髓增生异常综合征有时会发展为急性骨髓性白血病。MDS引起的细胞减少可导致严重的并发症，如出血、感染和症状性贫血。MDS患者的细胞遗传学异常对这些综合征的分类具有重要作用，对预测预后和治疗反应具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical Significance of Cytogenetics in Myelodysplastic Syndromes

The myelodysplastic syndromes (MDSs) are a heterogeneous group of diseases characterized by hemopoietic insufficiency associated with cytopenias due to dysfunctional hematopoietic stem cells. Myelodysplastic syndromes sometimes progress to acute myelogenous leukemia. The cytopenias caused by MDS lead to serious complications such as bleeding, infections, and symptomatic anemia. Cytogenetic abnormalities in MDS patients have an important role in categorizing these syndromes and are important in predicting prognosis and treatment response.

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来源期刊

Labmedicine 医学-医学实验技术

CiteScore

2.50

自引率

0.00%

发文量

155

审稿时长

>12 weeks

期刊介绍： Lab Medicine is a peer-reviewed biomedical journal published quarterly by the ASCP and Oxford University Press. The journal invites submission of manuscripts on topics related to clinical chemistry and microbiology, hematology, immunology, transfusion medicine, molecular diagnostics, cytology, histology, and laboratory administration and management. Original research, reviews, and case reports are considered for publication. Lab Medicine is indexed (under the title Laboratory Medicine) by the National Library of Medicine and is included in the PubMed database.