羧基碳纳米管功能化铜纳米粒子测定氯碱工人尿液和空气中的汞值及汞暴露对氧化应激的影响

Ali Faghihi zarandi, S. Karami-Mohajeri, Morteza Mehdipour Rabouri, Abbas Mohammadhosseini- Heyran, Z. Ahmadi
{"title":"羧基碳纳米管功能化铜纳米粒子测定氯碱工人尿液和空气中的汞值及汞暴露对氧化应激的影响","authors":"Ali Faghihi zarandi, S. Karami-Mohajeri, Morteza Mehdipour Rabouri, Abbas Mohammadhosseini- Heyran, Z. Ahmadi","doi":"10.24200/amecj.v5.i02.188","DOIUrl":null,"url":null,"abstract":"Mercury exposure can produce toxic organic compounds in the body. Also, mercury can potentially cause oxidative damage and cellular disorders. In this study, the determination of mercury values in urine and air of chloralkali workers based on copper nanoparticles functionalized in carboxylic carbon nanotubes (CuNPs@CNT-COOH) were obtained by cold vapor atomic absorption spectrometer (CV-AAS). The urine samples were determined by magnetic solid-phase extraction (MSPE) at pH 8.0. By measuring the mercury level in the air and the urine sample of workers, the level of oxidative stress (Malondialdehyde (MDA), Superoxide Dismutase (SOD) and Catalase (Cat)), Interleukin-6 (IL-6), and Tumor Necrosis Factor α (TNF-α) as the proinflammatory cytokines were measured in the subject group. The results revealed statistically significant differences in the mercury level of the urine samples in the case and control groups (p<0.001). Similarly, the malondialdehyde (MDA) level was significantly different between the two research groups (p<0.001). Catalase concentration was not significantly different in the two groups (p=0.059). The LOD and linear range for mercury determination in urine were achieved at 0.012 µg L−1 and 0.05-7.0 µg L−1, respectively. Workers’ exposure to mercury can significantly increase oxidative stress and inflammatory cell signaling molecules such as cytokines.","PeriodicalId":7797,"journal":{"name":"Analytical Methods in Environmental Chemistry Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Determination of mercury values in urine and air of chloralkali workers by copper nanoparticles functionalized in carboxylic carbon nanotubes and the effects of mercury exposure on oxidative stress\",\"authors\":\"Ali Faghihi zarandi, S. Karami-Mohajeri, Morteza Mehdipour Rabouri, Abbas Mohammadhosseini- Heyran, Z. Ahmadi\",\"doi\":\"10.24200/amecj.v5.i02.188\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Mercury exposure can produce toxic organic compounds in the body. Also, mercury can potentially cause oxidative damage and cellular disorders. In this study, the determination of mercury values in urine and air of chloralkali workers based on copper nanoparticles functionalized in carboxylic carbon nanotubes (CuNPs@CNT-COOH) were obtained by cold vapor atomic absorption spectrometer (CV-AAS). The urine samples were determined by magnetic solid-phase extraction (MSPE) at pH 8.0. By measuring the mercury level in the air and the urine sample of workers, the level of oxidative stress (Malondialdehyde (MDA), Superoxide Dismutase (SOD) and Catalase (Cat)), Interleukin-6 (IL-6), and Tumor Necrosis Factor α (TNF-α) as the proinflammatory cytokines were measured in the subject group. The results revealed statistically significant differences in the mercury level of the urine samples in the case and control groups (p<0.001). Similarly, the malondialdehyde (MDA) level was significantly different between the two research groups (p<0.001). Catalase concentration was not significantly different in the two groups (p=0.059). The LOD and linear range for mercury determination in urine were achieved at 0.012 µg L−1 and 0.05-7.0 µg L−1, respectively. Workers’ exposure to mercury can significantly increase oxidative stress and inflammatory cell signaling molecules such as cytokines.\",\"PeriodicalId\":7797,\"journal\":{\"name\":\"Analytical Methods in Environmental Chemistry Journal\",\"volume\":\"8 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical Methods in Environmental Chemistry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24200/amecj.v5.i02.188\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Methods in Environmental Chemistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24200/amecj.v5.i02.188","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

接触汞会在体内产生有毒的有机化合物。此外,汞可能会导致氧化损伤和细胞紊乱。本研究采用冷蒸汽原子吸收光谱仪(CV-AAS),建立了羧基碳纳米管(CuNPs@CNT-COOH)官能化铜纳米粒子对氯碱工人尿液和空气中汞的测定方法。采用磁固相萃取法(MSPE)在pH 8.0下测定尿液样品。通过测定空气中汞含量和工人尿液样本中汞含量,测定被试组氧化应激(丙二醛(MDA)、超氧化物歧化酶(SOD)、过氧化氢酶(Cat))、白细胞介素-6 (IL-6)、促炎细胞因子肿瘤坏死因子α (TNF-α)水平。结果显示,病例组和对照组尿液样本中的汞含量存在统计学上的显著差异(p<0.001)。同样,丙二醛(MDA)水平在两个研究组之间也有显著差异(p<0.001)。两组过氧化氢酶浓度差异无统计学意义(p=0.059)。尿液中汞的检出限和线性范围分别为0.012µg L−1和0.05 ~ 7.0µg L−1。工人接触汞会显著增加氧化应激和炎症细胞信号分子,如细胞因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determination of mercury values in urine and air of chloralkali workers by copper nanoparticles functionalized in carboxylic carbon nanotubes and the effects of mercury exposure on oxidative stress
Mercury exposure can produce toxic organic compounds in the body. Also, mercury can potentially cause oxidative damage and cellular disorders. In this study, the determination of mercury values in urine and air of chloralkali workers based on copper nanoparticles functionalized in carboxylic carbon nanotubes (CuNPs@CNT-COOH) were obtained by cold vapor atomic absorption spectrometer (CV-AAS). The urine samples were determined by magnetic solid-phase extraction (MSPE) at pH 8.0. By measuring the mercury level in the air and the urine sample of workers, the level of oxidative stress (Malondialdehyde (MDA), Superoxide Dismutase (SOD) and Catalase (Cat)), Interleukin-6 (IL-6), and Tumor Necrosis Factor α (TNF-α) as the proinflammatory cytokines were measured in the subject group. The results revealed statistically significant differences in the mercury level of the urine samples in the case and control groups (p<0.001). Similarly, the malondialdehyde (MDA) level was significantly different between the two research groups (p<0.001). Catalase concentration was not significantly different in the two groups (p=0.059). The LOD and linear range for mercury determination in urine were achieved at 0.012 µg L−1 and 0.05-7.0 µg L−1, respectively. Workers’ exposure to mercury can significantly increase oxidative stress and inflammatory cell signaling molecules such as cytokines.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.10
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信