1972 - 2010年阿拉伯马格里布国家马流感的血清学、分子特征和流行病学情况

IF 1.1 Q3 BIOLOGY
Mohamed Boukharta , Fathiah Zakham , Altaf Aloui , Nadia Touil , Mehdi Elharrak , Moulay Mustapha Ennaji
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引用次数: 2

摘要

马流感是马的一种传染性疾病。关于这一主题的研究在马格里布国家很少。因此,这项工作的目的是介绍自1972年以来在马格里布地区,特别是在摩洛哥、阿尔及利亚和突尼斯对血清学和分子马流感病毒进行的各种研究。在马格里布阿拉伯地区共分离出四种马流感毒株。A/equine/Nador/1/1997(H3N8), A/equine/Essaouira/2/2004(H3N8), A/equine/Essaouira/3/2004(H3N8)和A/equine/阿尔及尔/1/1972(H3N8)。A/马/纳多尔/1/1997(H3N8)与欧洲毒株HA核苷酸序列同源性最高:A/马/意大利/1199/1992(H3N8)和A/马/布雷西亚/1999(H3N8)与A/马/纳多尔/1/1997(H3N8)与欧洲毒株明显聚集。然而,A/equine/Algiers/1/1972(H3N8)、A/equine/Essaouira/2/2004(H3N8)和A/equine/Essaouira/3/2004(H3N8)被置于分化前谱系中,表明2004年类似的迈阿密/63菌株感染了摩洛哥的马科动物。这一发现并不能证实最近对马流感病毒H3N8亚型的研究,这些研究表明,在1990年之前流行的最古老的马H3N8毒株显然已经灭绝。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Serological, molecular characterization and epidemiological situation of equine influenza in the Arabic Maghreb countries between 1972 to 2010

Equine influenza is an infectious and contagious disease of horses. Studies on this topic are rare in the Maghreb countries. Therefore, the aim of this work is to present the various studies conducted on serological and molecular equine influenza virus since 1972 in the Maghreb region in particular in Morocco, Algeria and Tunisia.

A total of four equine influenza strains were isolated in the Maghreb Arab region. A/equine/Nador/1/1997(H3N8), A/equine/Essaouira/2/2004(H3N8), A/equine/Essaouira/3/2004(H3N8) and A/equine/Algiers/1/1972(H3N8).

The highest homology of HA nucleotide sequences of A/equine/Nador/1/1997(H3N8) with European strains: A/equine/Italy/1199/1992(H3N8) and A/equine/Brescia/1999(H3N8) clearly clustered A/equine/Nador/1/1997(H3N8) with the strains belonging to the European lineage. However, A/equine/Algiers/1/1972(H3N8), A/equine/Essaouira/2/2004(H3N8) and A/equine/Essaouira/3/2004(H3N8) were placed in the predivergent lineage indicating that like-Miami/63 strains infected equids in Morocco in 2004.

This finding does not corroborate the recent studies of the H3N8 subtype of equine influenza viruses which have demonstrated that the oldest equine H3N8 strains, circulating before 1990 apparently went extinct.

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