解码转移的复杂性。

Q2 Physics and Astronomy
Yingcheng Wu, Tiancheng Zhang, Xiaoming Zhang, Qiang Gao
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引用次数: 0

摘要

肿瘤转移仍然是肿瘤学中最令人困惑的问题之一1,2。尽管目前的尖端技术能够非常早地检测到肿瘤,但分析肿瘤是否已经开始扩散以及它试图在哪里定居仍然是一个主要障碍。事实上,转移播种事件表现出显著的时空异质性,其中起源(原发地点)和目的地(转移地点)是高度动态的。例如,肝转移尤其常见,并且仍然是导致死亡的主要原因。原发性癌症是多种多样的,可以包括胃肠道癌症,如结肠直肠癌和胰腺癌,以及腹腔外起源的癌症,如乳腺癌,其具有异质的临床表型和一系列治疗反应。由于现有的跨组织转移知识仍然很不完整,因此迫切需要生成统一的泛癌症转移图谱。从这个角度来看,我们概述了转移生物学的发展进展,重点介绍了在转移研究界使用高通量技术和最新理论所面临的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Decoding the complexity of metastasis.
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来源期刊
CiteScore
2.30
自引率
0.00%
发文量
0
期刊介绍: Journal of Theoretical and Applied Physics offers an exciting publication outlet for novel and frontier physics. It encourages the submission of new research on: condensed matter physics, theoretical physics, nonlinear science, statistical physics, mathematical and computational physics, general and cross-disciplinary physics (including foundations), atomic, molecular and cluster physics, plasma and fluid physics, optical physics, biological physics, nanoscience, laser and photonics, high energy and nuclear Physics. The journal''s high standard and wide dissemination ensures a broad readership amongst the physics community. Rapid publication times and flexible length restrictions give Journal of Theoretical and Applied Physics the edge over other journals in the field. Publishing in this journal is completely free of charge.
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