氯沙坦:减少腹水,但诱发癌症?美国国家科学院院刊又发表了一些愚蠢的声明!

G. Tchernev, I. Temelkova
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引用次数: 1

摘要

最近在PNAS-USA(美国国家科学院院刊)上发表的一篇论文中,同事们进行分析的主要目的是1)一方面关注氯沙坦在小鼠卵巢癌模型中的体外作用,证明氯沙坦的辅助作用对于平行诱导/或正在进行的化疗应该是绝对协同的,另一方面2)此外,回顾性观察患者组恶性腹水发生率似乎也有所减少[1]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Losartan: Reduces Ascites, but induces Cancer? Again Some Stupid Statements from PNAS- Proceedings of the National Academy of Science of USA!
The main purpose of the analyzes carried out by the colleagues in an recently published paper in PNAS-USA [Proceedings of the National Academy of Science of the United States of America) is focused 1) on the one hand on the in vitro effect of Losartan in murine ovarian carcinoma model, demonstrating that the adjuvant effect of losartan should be definitely synergistic with regard to the parallel-induced / or ongoing chemotherapy, and on the other hand 2) in addition, that malignant ascites in retrospectively observed patient group seems to be also reduced [1].
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