{"title":"非啮齿类动物重复给药90天口服毒性研究(OECD TG 409)","authors":"Tg","doi":"10.1787/9789264304741-32-en","DOIUrl":null,"url":null,"abstract":"922. This assay determines the general toxicity of chemicals in non-rodents after 90 days of oral dosing (by gavage, via the diet, in drinking water or in capsules). The most commonly used non-rodent species is the dog, which should be of a defined breed (beagle usually). It provides information on major toxic effects and target organ toxicity likely to arise from the post-weaning period until well into adulthood. OECD TG 409 was adopted in September 1981 and revised in September 1998.","PeriodicalId":19458,"journal":{"name":"OECD Series on Testing and Assessment","volume":"161 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents (OECD TG 409)\",\"authors\":\"Tg\",\"doi\":\"10.1787/9789264304741-32-en\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"922. This assay determines the general toxicity of chemicals in non-rodents after 90 days of oral dosing (by gavage, via the diet, in drinking water or in capsules). The most commonly used non-rodent species is the dog, which should be of a defined breed (beagle usually). It provides information on major toxic effects and target organ toxicity likely to arise from the post-weaning period until well into adulthood. OECD TG 409 was adopted in September 1981 and revised in September 1998.\",\"PeriodicalId\":19458,\"journal\":{\"name\":\"OECD Series on Testing and Assessment\",\"volume\":\"161 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"OECD Series on Testing and Assessment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1787/9789264304741-32-en\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"OECD Series on Testing and Assessment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1787/9789264304741-32-en","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents (OECD TG 409)
922. This assay determines the general toxicity of chemicals in non-rodents after 90 days of oral dosing (by gavage, via the diet, in drinking water or in capsules). The most commonly used non-rodent species is the dog, which should be of a defined breed (beagle usually). It provides information on major toxic effects and target organ toxicity likely to arise from the post-weaning period until well into adulthood. OECD TG 409 was adopted in September 1981 and revised in September 1998.
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