{"title":"低频电磁场和高频电磁场对人红细胞Ca2+转运有影响吗?","authors":"R Glaser, M Michalsky, R Schramek","doi":"10.1016/S0302-4598(98)00204-9","DOIUrl":null,"url":null,"abstract":"<div><p>In about 400 double experiments, the influence of electromagnetic fields between 15 Hz and 12 kHz on the active calcium pump (Ca,Mg-ATPase) of human erythrocytes was investigated. Each experiment includes the fitting of the efflux kinetics synchronously in two identical equipments, with two parts of the same erythrocyte suspension, one with field, one as untreated control. No clear effect on the activity of the Ca,Mg-ATPase of human erythrocytes could be found, neither for magnetic sinusoidal fields up to 2.6 mT (peak), nor for AC fields supported by a static magnetic field (3.9 mT SMF+3.9 mT, 1 kHz), nor for directly applied electric fields up to 150 V/m. The Arrhenius plot of the rate constants show a transition at 23°C, but no temperature-dependent field effect could be found. Several points, supported by 10 to 20 experiments show a small, but significant decrease in the rate constant of the efflux (45 Hz, 740 Hz, 1040 Hz), but this could not be confirmed by experiments at 620, 920 and 1540 Hz. The statistical deviation of the field effects in the region between 520 and 1540 Hz of the experiments with magnetic fields are significantly larger than for experiments with other frequencies and from such with the electrode system, whereas the deviation of the rate constants themselves are always the same.</p></div>","PeriodicalId":79804,"journal":{"name":"Bioelectrochemistry and bioenergetics (Lausanne, Switzerland)","volume":"47 2","pages":"Pages 311-318"},"PeriodicalIF":0.0000,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0302-4598(98)00204-9","citationCount":"7","resultStr":"{\"title\":\"Is the Ca2+ transport of human erythrocytes influenced by ELF- and MF-electromagnetic fields?\",\"authors\":\"R Glaser, M Michalsky, R Schramek\",\"doi\":\"10.1016/S0302-4598(98)00204-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In about 400 double experiments, the influence of electromagnetic fields between 15 Hz and 12 kHz on the active calcium pump (Ca,Mg-ATPase) of human erythrocytes was investigated. Each experiment includes the fitting of the efflux kinetics synchronously in two identical equipments, with two parts of the same erythrocyte suspension, one with field, one as untreated control. No clear effect on the activity of the Ca,Mg-ATPase of human erythrocytes could be found, neither for magnetic sinusoidal fields up to 2.6 mT (peak), nor for AC fields supported by a static magnetic field (3.9 mT SMF+3.9 mT, 1 kHz), nor for directly applied electric fields up to 150 V/m. The Arrhenius plot of the rate constants show a transition at 23°C, but no temperature-dependent field effect could be found. Several points, supported by 10 to 20 experiments show a small, but significant decrease in the rate constant of the efflux (45 Hz, 740 Hz, 1040 Hz), but this could not be confirmed by experiments at 620, 920 and 1540 Hz. The statistical deviation of the field effects in the region between 520 and 1540 Hz of the experiments with magnetic fields are significantly larger than for experiments with other frequencies and from such with the electrode system, whereas the deviation of the rate constants themselves are always the same.</p></div>\",\"PeriodicalId\":79804,\"journal\":{\"name\":\"Bioelectrochemistry and bioenergetics (Lausanne, Switzerland)\",\"volume\":\"47 2\",\"pages\":\"Pages 311-318\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0302-4598(98)00204-9\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioelectrochemistry and bioenergetics (Lausanne, Switzerland)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0302459898002049\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioelectrochemistry and bioenergetics (Lausanne, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0302459898002049","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Is the Ca2+ transport of human erythrocytes influenced by ELF- and MF-electromagnetic fields?
In about 400 double experiments, the influence of electromagnetic fields between 15 Hz and 12 kHz on the active calcium pump (Ca,Mg-ATPase) of human erythrocytes was investigated. Each experiment includes the fitting of the efflux kinetics synchronously in two identical equipments, with two parts of the same erythrocyte suspension, one with field, one as untreated control. No clear effect on the activity of the Ca,Mg-ATPase of human erythrocytes could be found, neither for magnetic sinusoidal fields up to 2.6 mT (peak), nor for AC fields supported by a static magnetic field (3.9 mT SMF+3.9 mT, 1 kHz), nor for directly applied electric fields up to 150 V/m. The Arrhenius plot of the rate constants show a transition at 23°C, but no temperature-dependent field effect could be found. Several points, supported by 10 to 20 experiments show a small, but significant decrease in the rate constant of the efflux (45 Hz, 740 Hz, 1040 Hz), but this could not be confirmed by experiments at 620, 920 and 1540 Hz. The statistical deviation of the field effects in the region between 520 and 1540 Hz of the experiments with magnetic fields are significantly larger than for experiments with other frequencies and from such with the electrode system, whereas the deviation of the rate constants themselves are always the same.