低频电磁场和高频电磁场对人红细胞Ca2+转运有影响吗?

R Glaser, M Michalsky, R Schramek
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引用次数: 7

摘要

在约400个双实验中,研究了15 Hz ~ 12 kHz电磁场对人红细胞活性钙泵(Ca, mg - atp酶)的影响。每个实验都包括在两个相同的设备上同步拟合流出动力学,同一红细胞悬浮液的两个部分,一个带场,一个作为未处理的对照。无论是2.6 mT(峰值)的正弦磁场,还是由静磁场支持的交流磁场(3.9 mT SMF+3.9 mT, 1 kHz),还是直接施加高达150 V/m的电场,都没有发现对人红细胞Ca, mg - atp酶活性的明显影响。速率常数的Arrhenius图显示在23℃时发生跃迁,但未发现温度场效应。10到20个实验支持的几个点表明,射流的速率常数(45 Hz、740 Hz、1040 Hz)有一个小而显著的下降,但这不能通过620、920和1540 Hz的实验来证实。在520 ~ 1540 Hz范围内,磁场实验的场效应统计偏差明显大于其他频率实验和电极系统的场效应统计偏差,而速率常数本身的偏差始终相同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is the Ca2+ transport of human erythrocytes influenced by ELF- and MF-electromagnetic fields?

In about 400 double experiments, the influence of electromagnetic fields between 15 Hz and 12 kHz on the active calcium pump (Ca,Mg-ATPase) of human erythrocytes was investigated. Each experiment includes the fitting of the efflux kinetics synchronously in two identical equipments, with two parts of the same erythrocyte suspension, one with field, one as untreated control. No clear effect on the activity of the Ca,Mg-ATPase of human erythrocytes could be found, neither for magnetic sinusoidal fields up to 2.6 mT (peak), nor for AC fields supported by a static magnetic field (3.9 mT SMF+3.9 mT, 1 kHz), nor for directly applied electric fields up to 150 V/m. The Arrhenius plot of the rate constants show a transition at 23°C, but no temperature-dependent field effect could be found. Several points, supported by 10 to 20 experiments show a small, but significant decrease in the rate constant of the efflux (45 Hz, 740 Hz, 1040 Hz), but this could not be confirmed by experiments at 620, 920 and 1540 Hz. The statistical deviation of the field effects in the region between 520 and 1540 Hz of the experiments with magnetic fields are significantly larger than for experiments with other frequencies and from such with the electrode system, whereas the deviation of the rate constants themselves are always the same.

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