A. Berger , C. Matei , P. Lallemant , P. Guiot , N. Bischoff , X. Delabranche
{"title":"对综合系统的止血和血管反应的接触阶段","authors":"A. Berger , C. Matei , P. Lallemant , P. Guiot , N. Bischoff , X. Delabranche","doi":"10.1016/S1297-9562(06)80010-0","DOIUrl":null,"url":null,"abstract":"<div><p>Contact system was thought to be an accessory pathway for thrombin generation. It appears that this system participate to fibrinolysis, vascular tone and capillary permeability regulation. These actions are mediated by FXII and bradykinin generated from high molecular weight kininogen. C1-inhibitor is the main regulatory protein. During cardiopulmonary bypass, activation of contact system occurs with secondary fibrinolysis, capillary leak syndrome and vasopl6gie. CI-inhibitor consumption leads to acquired deficit and therapeutic use may be of interest.</p></div>","PeriodicalId":100733,"journal":{"name":"ITBM-RBM","volume":"27 ","pages":"Pages S31-S34"},"PeriodicalIF":0.0000,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1297-9562(06)80010-0","citationCount":"0","resultStr":"{\"title\":\"Phase contact dans la réponse hémostatique et vasculaire vers un système intégré\",\"authors\":\"A. Berger , C. Matei , P. Lallemant , P. Guiot , N. Bischoff , X. Delabranche\",\"doi\":\"10.1016/S1297-9562(06)80010-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Contact system was thought to be an accessory pathway for thrombin generation. It appears that this system participate to fibrinolysis, vascular tone and capillary permeability regulation. These actions are mediated by FXII and bradykinin generated from high molecular weight kininogen. C1-inhibitor is the main regulatory protein. During cardiopulmonary bypass, activation of contact system occurs with secondary fibrinolysis, capillary leak syndrome and vasopl6gie. CI-inhibitor consumption leads to acquired deficit and therapeutic use may be of interest.</p></div>\",\"PeriodicalId\":100733,\"journal\":{\"name\":\"ITBM-RBM\",\"volume\":\"27 \",\"pages\":\"Pages S31-S34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1297-9562(06)80010-0\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ITBM-RBM\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1297956206800100\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ITBM-RBM","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1297956206800100","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Phase contact dans la réponse hémostatique et vasculaire vers un système intégré
Contact system was thought to be an accessory pathway for thrombin generation. It appears that this system participate to fibrinolysis, vascular tone and capillary permeability regulation. These actions are mediated by FXII and bradykinin generated from high molecular weight kininogen. C1-inhibitor is the main regulatory protein. During cardiopulmonary bypass, activation of contact system occurs with secondary fibrinolysis, capillary leak syndrome and vasopl6gie. CI-inhibitor consumption leads to acquired deficit and therapeutic use may be of interest.
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