卡他滨用于结肠癌的理论研究综述

Ganesh G. Dhakad, Rohit V. Chavan, Paresh A. Patil
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引用次数: 0

摘要

化疗是胃癌患者治疗的重要组成部分。虽然对于晚期疾病患者没有全球公认的单一护理标准,但治疗方案通常包括氟嘧啶和铂化合物,有或没有第三种药物(通常是表柔比星或多西他赛)。口服氟嘧啶,如卡培他滨,在便利性方面为患者提供了明显的优势,但直到最近才有关于其在胃癌患者中的疗效和安全性的全面数据。本文综述了卡培他滨在晚期胃癌和可切除胃癌治疗中的应用。正在进行的涉及卡培他滨的III期试验也进行了讨论。数据显示,卡培他滨现已成为胃癌患者多药治疗方案中不可或缺的一部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review on Theoretical Study of Capacitabine use in Colon Cancer
Chemotherapy is an important part of treatment for patients with gastric cancer. Although there is no single globally accepted standard of care for patients with advanced disease, regimens typically include a fluoropyrimidine and a platinum compound with or without a third drug (usually epirubicin or docetaxel). Oral fluoropyrimidines, such as capecitabine, offer clear advantages to patients in terms of convenience, but it is only recently that comprehensive data on their efficacy and safety in patients with gastric cancer have become available. The present article reviews capecitabine in the treatment of advanced and resectable gastric cancer. Ongoing Phase III trials involving capecitabine are also discussed. The data show that capecitabine is now established as an integral part of the multi-agent regimens used in the management of patients with gastric cancers.
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