Synthesis and Characterization of Some Hydroxylated Chalcones by using BF3.Et2O via Claisen-Schmidt Condensation

Indian spices that provide flavor, color, and aroma to food also possess many therapeuticproperties. So the present study was aimed to extract the phytochemical compounds in Pipercubeba, used as food fortifiers. The extract was investigated for the richness of its bioactivecompounds. The aqueous of P. cubeba extract was subjected to sensitive gas chromatography– mass spectroscopy GC-MS analysis revealed 10 chemical constituents. Extract exhibits potentially bioactive major constituents like Cyclohexanol, Carbamic acid, p-Methoxyamphetamine, Bioxirane and Linalol. Further presented the total carbohydrate, elements, such as Ca, Mg, Se, K and Fe were in highest proportion in the aqueous extract ofPiper cubeba. The aqueous extract was injected to HPLC to detect the phenolic compounds inthe extract like Gallic acid, Caffeic acid,Syringic acid, Ferulicacid,Rutin and Catechin. Wehave investigated the antimicrobial activity of water extract from P. Cubeba against majorskin pathogens Staphylococccus aureus, Pseudomonas aeruginosa , Proteus vulgaris andKoucria rosia. . The presence of some phytochemicals (saponins, alkaloids, flavonoids,cardiac glycosides, tannins and terpenoids) and some essential minerals proves that it is reallyan alternative source of medicine.