《中美妊娠期甲状腺疾病诊治指南》解读

Jiang Bohua, Tao Xinli, Ouyang Zhenbo, Yan Jiane
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摘要

越来越多的研究发现甲状腺毒症和甲状腺功能减退与不良妊娠结局有关,母体甲状腺疾病对胎儿发育也有一定影响。用于治疗母体甲状腺功能亢进的药物可通过胎盘,影响胎儿甲状腺发育和甲状腺功能,并可能导致胎儿发育畸形。由于对该病认识不够深入,妊娠期甲状腺疾病的及时筛查、求诊和治愈率相对较低。像这样,如果治疗不及时,可能会对妊娠过程和胎儿造成不可逆的影响,如增加妊娠期高血压、流产、早产、低出生体重、死胎、甲状腺危象和母体充血性心力衰竭的风险,损害后代的神经和智力发育。本文拟通过对2020年中美两国最新的孕期甲状腺疾病诊疗指南的对比分析,为临床医生对孕期及产后甲状腺疾病的规范化诊疗提供参考。希望通过本文,减少甲状腺功能异常对母亲、胎儿和妊娠的各种相关并发症和风险,提高人群素质。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Interpretation of Chinese and American Guidelines for Diagnosis and Treatment of Thyroid Diseases During Pregnancy
More and more studies have found that thyrotoxicosis and hypothyroidism are related to adverse pregnancy outcomes, and maternal thyroid diseases also have a certain impact on fetal development. Drugs used to treat maternal hyperthyroidism can pass through the placenta and affect fetal thyroid development and thyroid function, and may cause fetal development malformations . Due to the lack of in-depth knowledge of this disease, timely screening, medical consultation and treatment rates for thyroid diseases during pregnancy are relatively low. Like this, if the treatment is not timely, it may cause irreversible effects on the pregnancy process and the fetus, such as increasing the risk of high blood pressure during pregnancy, miscarriage, premature delivery, low birth weight, stillbirth, thyroid crisis and maternal congestive heart failure, and impairing the neurological and intellectual development of offspring. This article intends to provide a reference for clinicians in the standardized diagnosis and treatment of thyroid diseases during pregnancy and postpartum through a comparative analysis of the latest guidelines for the diagnosis and treatment of thyroid diseases during pregnancy in China and the United States in 2020. It is hoped that through this article, various related complications and risks of mothers, fetuses and pregnancy caused by abnormal thyroid function will be reduced, and the quality of the population will be improved.
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