磺胺类抗菌药物的研究进展

Sonu, B. Parveen, S. Praveen, H. Pal
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引用次数: 3

摘要

磺胺类化合物是一种含有- so2nh2和/或- so2nh -基团的有机含硫化合物。磺胺类或磺胺类药物竞争性地抑制微生物中叶酸的合成,随后抑制细菌的繁殖,但不主动杀死它们。它们已被用于对付大多数革兰氏阳性和许多革兰氏阴性细菌、一些真菌和某些原生动物。医学上重要的磺胺类物质
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A short review on sulphonamides with antimicrobial activity
Sulfonamides are one of the organosulphur compounds containing the -SO 2 NH 2 and/or -SO 2 NH- group(s). The sulphonamides or sulfa drugs competitively inhibit folic acid synthesis in micro-organisms and subsequently inhibit multiplication of bacteria but do not actively kill them. They have been used against most gram-positive and many gram-negative bacteria, some fungi, and certain protozoa. Medically important sulphonamides
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