腺瘤-癌序列的临床证据。

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation Pub Date : 1999-12-01 DOI:10.1097/00008469-199912001-00011

O. Kronborg, C. Fenger

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引用次数: 38

摘要

综述了支持或反对结直肠腺瘤-癌序列假说的证据。大多数研究从临床角度讨论腺瘤，但病理学也被详细考虑，分子生物学也被触及。结论:腺瘤期很可能是向癌发展的一个阶段。但从长远来看，腺瘤的切除对结直肠癌的发病率有什么影响还有待观察。

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Clinical evidence for the adenoma-carcinoma sequence.

A review is given on evidence supporting or rejecting the hypothesis of a colorectal adenoma-carcinoma sequence. The majority of studies discuss adenomas from a clinical point of view, but pathology has also been considered in detail, and molecular biology has been touched on. It is concluded the adenoma stage is, most probably, a phase on the way to carcinoma. But it remains to be shown what effect the removal of adenomas will have in the long run on the incidence of colorectal carcinoma.

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European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation

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