奥里萨邦布巴内斯瓦尔三级保健中心头颈部病变的细胞形态学和组织病理学相关性研究

Anima Hota, Pranita Mohanty, Mitu Mohanty
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摘要

头颈部是一个解剖部位,有淋巴结、神经、静脉、动脉、肌肉、粘膜上皮、唾液腺、甲状腺和许多发育组织。这些组织中的任何一个都可能变成病理性的,导致肿块。细针吸细胞学(FNAC)被认为是头颈部病变诊断的可靠方法。然而,组织病理学是诊断的金标准。本研究的目的是根据其发生部位评估头颈部肿瘤的发生频率,并探讨FNAC细胞病理学检查结果与活检组织病理学检查结果的相关性。方法本前瞻性研究于2012年6月至2014年6月在布巴内斯瓦尔三级保健中心IMS和SUM医院病理学系进行。所有在布巴内斯瓦尔IMS & SUM医院就诊的头颈部病变患者均被纳入研究。将FNAC结果与组织活检病理结果进行比较。收集的数据在MS Excel中输入,并使用相同的软件进行分析。描述性统计度量,如频率和百分比。数据以表格形式呈现。结果病变部位以淋巴结最常见,其次为甲状腺。甲状腺病变以女性居多,其他部位以男性居多。良、恶性病变的细胞-组织病理学相关性准确率分别为96.36%和88.89%,其中甲状腺病变的准确率最高(50.6%)。结论头颈部病变的细胞组织相关性检查是一种重要、快速、优良、灵敏的诊断工具,可将非肿瘤性病变与肿瘤性病变区分开来。关键词头颈部病变,FNAC,组织病理学
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Study on Cytomorphological and Histopathological Correlation of Head and Neck Lesions in a Tertiary Care Centre, Bhubaneswar, Odisha
BACKGROUND The head and neck region is an anatomic site having lymph nodes, nerves, veins, arteries, muscles, mucosal epithelium to salivary glands, thyroid, and a host of developmental tissues. Any of these tissues can become pathological, resulting in a mass. Fine needle aspiration cytology (FNAC) is regarded as a reliable method of investigation in diagnosis of head and neck lesions. However, histopathology is the gold standard of diagnosis. The purpose of this study was to assess the frequency of head and neck tumours according to the sites of their occurrence and to find out the correlation of cytopathological findings by FNAC and histopathological findings by biopsy. METHODS This prospective study undertaken from June 2012 to June 2014 in the Department of Pathology, IMS and SUM Hospital, Bhubaneswar, a tertiary care center. All the patients attending different outdoor of IMS & SUM Hospital, Bhubaneswar with head & neck lesions referred for FNAC were included in the study. The results of FNAC were compared with that of histopathological findings by tissue biopsy. Data collected was entered in MS Excel and analysed using the same software. Descriptive statistical measures like frequency and percentage. Data was presented in tabular form. RESULTS The commonest site of lesion was in the lymph node followed by thyroid gland. There was preponderance of female sex in thyroid lesions whereas males were commonest in other sites. The accuracy in cyto-histopathology correlation between benign and malignant lesion was 96.36 % and 88.89 % respectively and was most corroborated in the thyroid lesions (50.6 %). CONCLUSIONS Cyto-histo correlation of head and neck lesions provides an important, quick, excellent, and sensitive diagnostic tool to exclude non-neoplastic lesions from neoplastic lesions. KEYWORDS Head and Neck Lesions, FNAC, Histopathology
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