Nicholas Hanuscheck, Carine Thalman, M. Domingues, Samantha Schmaul, M. Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, G. Martino, T. Kuhlmann, K. Bozek, Tim van Beers, S. Bittner, Jakob von Engelhardt, J. Vogt, C. Vogelaar, F. Zipp
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Neuroimmune interaction influences essential CNS processes. Hanuscheck et al. report on the expression of interleukin-4 receptor alpha at presynaptic terminals in mouse and the human brain. The modulation of neuronal IL-4R signaling alters the neuronal transcriptome, impacts synaptic transmission, and causes anxiety-related behavior.
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