{"title":"从糖尿病患者中分离肺炎克雷伯菌的几种致病因子的表型和遗传学研究","authors":"S. Mohammed, Nibras Y. Abdulla","doi":"10.21608/eajbsc.2023.309053","DOIUrl":null,"url":null,"abstract":"Klebsiella pneumoniae is the most frequent cause of nosocomial and community-acquired infections. The virulence factors help Klebsiella pneumoniae establish an infection in the human body by contributing to its ability to survive in a variety of environmental circumstances. 42 K. pneumoniae clinical specimens were isolated from diabetic patients suffering from urinary tract infection and diabetic foot ulcer in this study. K.pneumoniae virulence factors are currently being identified using phenotypic and genotypic approaches. The K. pneumoniae isolates that were positive for several virulence factors included 33 (78.6%) capsule, 17 (40%) hypermucoviscosity development, 14 (33.3%) proteases, and none were positive for hemolysis . K. pneumoniae isolates had a virulence gene that was 15% wcaG, 60% entB, and negative for rmpA.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"60 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Studying Several Virulence Factors Phenotypically and Genetically to Isolate Klebsiella Pneumonia from Diabetic Patients\",\"authors\":\"S. Mohammed, Nibras Y. Abdulla\",\"doi\":\"10.21608/eajbsc.2023.309053\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Klebsiella pneumoniae is the most frequent cause of nosocomial and community-acquired infections. The virulence factors help Klebsiella pneumoniae establish an infection in the human body by contributing to its ability to survive in a variety of environmental circumstances. 42 K. pneumoniae clinical specimens were isolated from diabetic patients suffering from urinary tract infection and diabetic foot ulcer in this study. K.pneumoniae virulence factors are currently being identified using phenotypic and genotypic approaches. The K. pneumoniae isolates that were positive for several virulence factors included 33 (78.6%) capsule, 17 (40%) hypermucoviscosity development, 14 (33.3%) proteases, and none were positive for hemolysis . K. pneumoniae isolates had a virulence gene that was 15% wcaG, 60% entB, and negative for rmpA.\",\"PeriodicalId\":52600,\"journal\":{\"name\":\"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology\",\"volume\":\"60 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/eajbsc.2023.309053\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/eajbsc.2023.309053","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Studying Several Virulence Factors Phenotypically and Genetically to Isolate Klebsiella Pneumonia from Diabetic Patients
Klebsiella pneumoniae is the most frequent cause of nosocomial and community-acquired infections. The virulence factors help Klebsiella pneumoniae establish an infection in the human body by contributing to its ability to survive in a variety of environmental circumstances. 42 K. pneumoniae clinical specimens were isolated from diabetic patients suffering from urinary tract infection and diabetic foot ulcer in this study. K.pneumoniae virulence factors are currently being identified using phenotypic and genotypic approaches. The K. pneumoniae isolates that were positive for several virulence factors included 33 (78.6%) capsule, 17 (40%) hypermucoviscosity development, 14 (33.3%) proteases, and none were positive for hemolysis . K. pneumoniae isolates had a virulence gene that was 15% wcaG, 60% entB, and negative for rmpA.