在波兰,her阳性乳腺癌患者很少进行保乳手术

Q4 Medicine
Nowotwory Pub Date : 2020-12-04 DOI:10.5603/njo.2020.0047
Joanna Kufel-Grabowska, B. Radecka, J. Streb, A. Jagiełło-Gruszfeld, J. Hudała-Klecha, E. Szombara, R. Sienkiewicz, B. Czartoryska-Arłukowicz, Piotr Witasik, Katarzyna Sokołowska, W. Wysocki
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引用次数: 3

摘要

乳腺癌是波兰和全世界妇女中最常见的癌症;它是女性恶性肿瘤患者死亡的第二大原因,仅次于肺癌。HER2阳性乳腺癌约占所有病例的15 - 20%。与其他亚型相比,它更常影响年轻患者,并且更常扩散转移到内脏器官。针对HER2受体的新药显著改善了患者的预后,无论初始阶段如何。该研究的作者纳入了1503例所有阶段(I-IV期)的HER2阳性乳腺癌患者;482例患者术前接受全身治疗(化疗或激素治疗),385例接受曲妥珠单抗。1219例符合手术条件的女性患者中,734例(60%)行乳房切除术,485例(40%)行保乳加辅助放疗,部分患者术前行全身治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Breast-conserving surgeries in HER-positive breast cancer patients are performed too rarely in Poland
Breast cancer is the most common cancer among women in Poland and worldwide; after lung cancer it is the second highest cause of death among females with malignancies. HER2 positive breast cancer occurs in ca.15–20% of all cases. More often than other subtypes, it affects younger patients and more often spreads metastasises to internal organs. The new drugs against the HER2 receptor significantly improve patients’ prognoses, regardless of the initial stage. The authors of the study involved 1503 patients with HER2 positive breast cancer from all stages (I–IV); 482 patients received preoperative systemic therapy (chemotherapy or hormonal therapy), 385 trastuzumab. Among the 1219 females qualified to surgery, 734 (60%) underwent a mastectomy, 485 (40%) had breast conserving therapy with adjuvant radiotherapy, some of them had preoperative systemic treatment.
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来源期刊
Nowotwory
Nowotwory Medicine-Oncology
CiteScore
0.90
自引率
0.00%
发文量
44
期刊介绍: NOWOTWORY Journal of Oncology publishes papers which cover all aspects of oncology but concentrates on clinical studies, both research orientated and treatment orientated, rather than on laboratory studies. Contributions are also welcomed from the fields of epidemiology, tumor pathology, radiobiology and radiation physics.
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