脑磁图分析皮特斯拉经颅磁刺激对癫痫患者影响的频率

P. Anninos
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引用次数: 3

摘要

本研究的目的是确定癫痫患者在皮特斯拉经颅磁刺激(pT-TMS)后大脑状态中2-7Hz频率的变化。这是一种治疗神经系统疾病的非侵入性技术。在低磁噪声的磁屏蔽室内,采用全头部122通道脑磁图系统对10例癫痫患者进行脑磁图记录。研究对象为5男5女,年龄在18-42岁之间。随后对上述患者行体外pT-TMS治疗。为了检测应用pT-TMS前后从每个患者和通道获得的MEG功率谱的主主频率,我们在实验室开发了一个软件程序。我们发现10例患者中有7例(70%)在应用pT-TMS后其2-7Hz频率增加。我们得出结论,频率分析是一种很有前途的癫痫疾病评估手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency Analysis for The Effect of Pico Tesla-Transcranial Magnetic Stimulation in Epilepsy Patients Using Magnetoencephalography
The purpose of this research is to identify any change in the frequencies of 2-7Hz in the brain state of epilepsy patients after pico-Tesla transcranial magnetic stimulation (pT-TMS). It is a noninvasive technique for treating neurological disorders. We used magneto encephalographic (MEG) recordings of 10 epilepsy patients with a whole-head 122 channel MEG system in a magnetically shielded room of low magnetic noise. The subjects were 5 male and 5 female epilepsy volunteers between 18-42 years of age. Afterwards, external pT-TMS was applied to the above patients. A software program was developed in our lab in order to detect the primary dominant frequency of the power spectra of the MEG obtained from every patient and channel before and after the application of pT-TMS. We found that 7 out of 10 patients (70%) had increased their 2-7Hz frequencies after the application of pT-TMS. We concluded that frequency analysis is a promising means for the assessment of epilepsy disorders.
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