Chemical composition and biological activity of metabolites of Rubus chamaemorus L.

 The article describes the climatic conditions and the geographical zones of cloudberry (Rubus chamaemorus L.) growth. A trend towards cultural and semi-cultural cultivation of this species was noted. The current state of research on the chemical composition of various parts of cloudberry squat, growing in various environmental conditions, is highlighted. A systematic assessment of accumulation of biologically active substances (vitamins, fatty acids, flavonoids, anthocyanins, proanthocyanidins, phenolic acids) of this plant of northern and southern populations was carried out. The role of secondary metabolites in the formation of the biological potential of R. chamaemorus L. fruits and leaves is described. High antioxidant and antiradical activities of cloudberry fruit extracts in in vitro and in vivo model systems are also noted. The review presents the results of scientific works devoted to the study of the antimicrobial activity of fruits against Helicobacter pillory, Staphylococcus aureus, Staphylococcus epidermis, Bacillus subtilis, Campylobacter jejuni, Micrococcus luteus, Escherichia coli, Candida albicans. There is a lack of research of secondary metabolites of the plant on the southern border of the range. The biological significance of fruits and ground leaf mass, as well as the prospects for cultivation on the southern border of the range and their practical use in the pharmaceutical and food industries are highlighted.