与COVID-19感染相关的后部可逆性脑病综合征(PRES) -1例报告与回顾

Shamik Shah, U. Patel, Neev Mehta, Pratik Shingru
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引用次数: 1

摘要

2019冠状病毒病(COVID-19)引起了包括各种神经系统并发症在内的大量全身并发症。一些神经系统并发症尚不清楚。后可逆性脑病综合征(PRES)是一种已知的急性神经毒性综合征,可引起广泛的神经系统症状。如果不及时治疗,它可能会成为危及生命的疾病。然而,它不是COVID-19的已知神经系统并发症。我们描述了一位COVID-19阳性患者的PRES表现,并表现为精神状态改变。78岁男性,有特发性癫痫病史,因呼吸系统疾病入院,COVID-19检测阴性。在住院期间,他的呼吸系统状况恶化,再次进行COVID-19检测呈阳性。他一直有脑病,后来被发现有癫痫持续状态。脑磁共振成像显示广泛的press相关改变。他的血压总体保持在控制范围内,没有明显波动。除可能与COVID-19相关外,未发现PRES的其他明显病因。临床医生在鉴别诊断伴有持续性脑病的重症COVID-19患者时应尽早考虑PRES。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Posterior Reversible Encephalopathy Syndrome (PRES) Associated With COVID-19 Infection—A Case Report and Review
Coronavirus disease 2019 (COVID-19) has caused a large number of systemic complications including a variety of neurological complications. Some of the neurological complications are not known. Posterior reversible encephalopathy syndrome (PRES) is a known acute neurotoxic syndrome causing a wide range of neurological symptoms. If remains untreated, it can potentially become a life-threatening condition. However, it is not a known neurological complication of COVID-19. We describe a presentation of PRES in a patient with positive COVID-19 and presented with altered mental status. A 78-year-old male with history of idiopathic epilepsy was initially admitted with respiratory illness with negative COVID-19 test. Later during his hospitalization, his respiratory condition got worse and his repeat COVID-19 test came back positive. He had continued encephalopathy and was found to have status epilepticus afterward. Magnetic Resonance Imaging brain showed extensive PRES-related changes. His blood pressure remained overall within control without significant fluctuations. No other apparent etiology was identified for PRES except for possible correlation with COVID-19. Clinicians should consider PRES early in their differential diagnoses in patients with severe COVID-19 with continued encephalopathy.
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