循环肿瘤DNA分析:从发现到临床应用

Q4 Health Professions

中华检验医学杂志 Pub Date : 2020-02-11 DOI:10.3760/CMA.J.ISSN.1009-9158.2020.02.001

Rui Zhang

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引用次数: 0

摘要

循环肿瘤DNA分析是临床研究的热点问题。一些生物标志物已用于临床实践，而一些则处于发现阶段。将讨论循环肿瘤DNA分析从发现到临床实践的过程中，临床实验室面临的主要挑战，包括基于临床有效性和效用的证据选择预期用途，测试过程的质量保证，结果的报告和解释。关键词:循环肿瘤DNA;临床检验技术;生物标记物

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Circulating tumor DNA analysis:from discovery to clinical practice

Circulating tumor DNA analysis is the focused issue in clinical research. A few of biomarkers have been used in clinical practice, while some are in the discovery phase. The key challenges for clinical laboratories on the way from discovery to clinical practice of the circulating tumor DNA analysis, including choosing the intended use based on evidence for clinical validity and utility, quality assurance for the testing process, reporting and interpretation for the results will be discussed. Key words: Circulating tumor DNA; Clinical laboratory techniques; Biomarkers

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来源期刊

中华检验医学杂志 Health Professions-Medical Laboratory Technology

CiteScore

0.40

自引率

0.00%

发文量

8037

期刊介绍：