米索前列醇应用于无痛人工流产前后的临床观察

Yu Cai, Huilian Huang, J. Zhai, Bi-bo Feng
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引用次数: 0

摘要

背景:无痛人工流产是一种安全、有效、优良的人工流产方法,但静脉麻醉不能有效扩张宫颈。宫颈硬紧常影响手术,易诱发流产并发症。米索前列醇能诱导子宫收缩,软化子宫颈。目的:探讨米索前列醇在无痛人工流产前后的临床疗效。方法:600例孕妇分为A、B、C三组,每组200例。所有患者均麻醉。A组患者于人工流产手术前2小时于阴道后穹窿内放置米索前列醇0.2 ug;B组米索前列醇0.2 ug不仅在人工流产术前2 h滴入阴道后穹窿内,而且在术后2 h和6 h口服;C组术前、术后均不使用米索前列醇。比较三组患者的手术时间、术中出血量、术后出血量、宫颈松弛率及不完全流产率。结果:与A、B组比较,C组手术时间更长,出血量更多(P < 0.05)。结论:无痛人工流产前后应用米索前列醇不仅可以缩短手术时间,减少术中及术后阴道出血,而且没有发生不完全流产(主要结局)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Observation of Misoprostol before and after Painless Induced Abortion
Background: Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. Hard and tight cervix often affects the operation and easily inducesabortion complications. Misoprostol can induce uterine contraction and soften the cervix. Objective: To investigate the clinical effect of misoprostol on abortion before and after painless induced abortion. Methods: 600 case pregnant women were divided into three groups: A, B and C, 200 case in each group. All patients were anesthetized. In group A, misoprostol 0.2 ug was placed in the posterior fornix of vagina 2 hours before the operation of induced abortion; in group B, misoprostol 0.2 ug was not only placed in the posterior fornix of vagina 2 hours before the operation of induced abortion but also taken orally 2 hours and 6 hours after the operation; in group C, misoprostol was not used before and after the operation. The operation time, intraoperative bleeding volume, postoperative bleeding, the percentage of cervical relaxation and the rate of incomplete abortion among the three groups were compared. Results: Compared with group A and group B, the operation time of group C was longer and the amount of bleeding was more (P 0.05). The duration of bleeding in group B was less than that in group A (P Conclusion: The use of misoprostol before and after painless induced abortion can not only shorten the time of operation, reduce intraoperative and postoperative vaginal bleeding, but also has not incurred incomplete abortion(primary outcome).
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