M. Firrincieli, L. Maiorana, A. Cappello, G. Lo Presti, A. Lucenti, C. Lancia, D. Di Noto, S. Cordio
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摘要

背景:2020年12月,由于美国肿瘤学会、意大利罗氏公司和我们协会之间的合作,在西西里岛的ASP 7 Ragusa建立了一个名为“HER Home”的抗肿瘤治疗定居项目。该项目涉及HER2阳性乳腺癌患者,涉及在家中进行皮下抗母细胞治疗。目的包括提高患者的生活质量,减少旅行和访问医院的需要,使他们更舒适地接受治疗。在目前的大流行形势下,这意味着对脆弱的受试者和可能更容易受到感染的患者有更大的安全保障;同时也意味着提高组织效率。材料和方法:根据制定治疗计划和开药的肿瘤内科医生的评估,患者入院。该药由医院药房配制。本协会已积极开展家庭缓和治疗,负责将药物从医院药房运送到患者家中,由我们的医生在对患者进行临床评估后给药。该项目预计将有20名妇女和约240个行政部门参与。生活质量将在基线和每4次给药时进行评估,使用患者自我报告的结果测量(PROMs)。结果:迄今为止,共协助4例患者进行了13次给药。未发生不良事件,也未记录组织关键问题。所有的管理是安全的,在预见的时间和方法。结论:该项目使患者有更多的自由时间,因为不需要在日间医院转院和等待时间,因此允许他们不改变日常生活的进程;我们也期望生活质量得到可衡量的改善。对于区域卫生系统而言,该项目简化了通道,减少了医院的拥挤程度,这在2019冠状病毒病大流行期间至关重要。从经济角度来看,该项目降低了成本,所需资源减少了30%左右。这个初步项目所显示的潜力可以在评估家庭管理其他抗肿瘤疗法的可能性时充分实现,这些疗法首先有利于那些工作和家庭生活非常活跃的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AIOM abstracts
Background: In December 2020, thanks to the collaboration among the U.O.C. Oncologia, Roche Italia, and our Association, was set up a project for the domiciliation of antiblastic treatment titled “HER Home”, at the ASP 7 Ragusa in Sicily. The project involving patients with HER2 positive breast cancer concerns treatment at home with subcutaneous antiblastic therapy. Aims include the enhancement of patients' quality of life reducing the need for travel and visits to the hospital and making them more comfortable to receive the therapy. During the current pandemic situation, this means a greater safety for patients who are fragile subjects and may be more exposed to the risk of infection;and, also, the improvement in organizational efficiency. Materials and methods: Admission of patients takes place according to the evaluation of the Medical Oncologists who establish the schedule of treatments and prescribe the drug. The drug is prepared and dispensed by the hospital pharmacy. Our Association, already active for home palliative care, deals with the transport of the drug from the hospital pharmacy to the patients' home, where our Doctor, after a clinical evaluation of the patient, administers the drug. The project foresees the participation of 20 women and about 240 administrations. Quality of life will be assessed at baseline and every 4 administrations, using patient's self-reported outcome measures (PROMs). Results: To date, have been assisted 4 patients and carried out 13 administrations. No adverse events have occurred and no organizational criticalities were recorded. All administrations were performed safely, within the foreseen times and methods. Conclusions: The project has allowed the patients involved to have more free time since there are no needs for transfers and waiting times in the Day Hospital and so allowing them don't change the course of their daily routine;we, also, expect a measurable improvement in the quality of life. For the regional health system, this project achieved a simplification of the pathways and a reduction in the crowding of the Hospital, both essential during the COVID-19 pandemic. From the economic point of view, the project reduced costs and resources applied for about 30% less. The potential shown by this preliminary project could be fully realized in the evaluation of the possibility of home administration of other antiblastic therapies favoring above all the patients who lead a very active working and family life.
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