Antimicrobial potential of a gel containing hydrogen peroxide and hyaluronic acid (Letter)

Although biocidal action of hydrogen peroxide (HPO) is not well understood, many authors believe that the free hydroxyl radicals causes oxidation of DNA, proteins and lipid membranes (Linley et al., 2012). Use of HPO on skin problems is recently gaining importance due to its efficacy in preventing acne (Milani et al., 2003; Veraldi et al., 2016).It is also being used in treating Molluscum contagiosum due to its antiviral properties (Schianchi et al., 2018). Hyaluronic acid (HA) is another product with promising skin benefits because of its moisturising and wound healing properties, along with its ability to prevent wrinkles (Lee et al., 2015). It also produces extracellular matrix and prevents infections by modulating cellular immunity (Jegasothy et al., 2014). There are also clinical studies that tested the effectiveness of HA on skin, particularly in decreasing the depth of wrinkles, hydrating the skin and improving the firmness and elasticity of the skin (Jegasothy et al., 2014; Lee et al., 2015; Pavicic et al., 2011).