60岁以下患者髋部下骨折早期与延迟固定的比较

R. Jain, Manfred Koo, H. Kreder, Emil H. Schemitsch, J. Davey, N. N. Mahomed
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引用次数: 189

摘要

背景:年轻患者的髋部下骨折通常采用内固定治疗,而不是原发性半关节置换术,后者通常用于年龄较大、需求低的患者。由于股骨头供血中断,损伤后可发生缺血性坏死。一些人认为急诊骨折复位是必要的,以尽量减少缺血性坏死的风险。本研究的目的是:(1)研究60岁或以下患者髋部下骨折的功能结局;(2)比较早期和延迟骨折固定后缺血性坏死的发生率。方法:这项回顾性研究纳入了60岁或以下接受髋部下骨折复位和内固定治疗的成年人,并对他们进行了至少两年的临床随访。患者分为两组:早期固定组(损伤后12小时内)和延迟固定组(损伤后12小时以上)。使用Short Form-36和Western Ontario and McMaster University (WOMAC)骨关节炎指数评估功能结果。比较两组无血管坏死发生率。结果:38例患者参与研究,平均年龄46.4岁。29例患者发生移位性髋关节下骨折。15例患者接受早期骨折固定,其余患者接受延迟固定。在早期和延迟固定组之间,Short Form-36评分(p = 0.68)或WOMAC评分(p = 0.69)无差异。6例接受延迟内固定治疗的患者出现了血管坏死的影像学证据,其中1例术前有未移位骨折,没有患者接受早期内固定治疗。两组无血管坏死发生率差异有统计学意义(p = 0.03)。结论:尽管延迟手术治疗的髋关节下骨折与较高的缺血性坏死率相关,但这种并发症并未显著影响功能预后。需要更长时间的随访来评估无血管坏死对关节炎发展和患者长期功能的影响。尽管结果可能存在偏差,因为患者没有被随机分配到延迟或早期固定,但数据表明,在高需求患者发生移位性髋下骨折后12小时内紧急复位和骨折固定可能与减少无血管坏死的影像学迹象有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Early and Delayed Fixation of Subcapital Hip Fractures in Patients Sixty Years of Age or Less
Background: Subcapital hip fractures in younger patients are generally treated with internal fixation rather than with primary hemiarthroplasty, which is generally reserved for older, low-demand patients. Avascular necrosis can occur following this injury because of disruption of the femoral head blood supply. Some believe that emergent fracture reduction is necessary to minimize the risk of avascular necrosis. The purposes of this study were (1) to investigate the functional outcomes of subcapital hip fractures in patients sixty years old or younger and (2) to compare the rates of avascular necrosis after early and delayed fracture fixation.Methods: This retrospective study included adults in whom a subcapital hip fracture had been treated with reduction and internal fixation when they were sixty years of age or less and who had been followed clinically for a minimum of two years. The patients were divided into two groups: those treated with early fixation (within twelve hours after the injury) and those treated with delayed fixation (more than twelve hours after the injury). Functional outcomes were assessed with use of the Short Form-36 and the Western Ontario and McMaster University (WOMAC) Osteoarthritis Index. The rates of avascular necrosis were compared between the two groups.Results: Thirty-eight patients (average age, 46.4 years) participated in the study. Twenty-nine patients had a displaced subcapital hip fracture. Fifteen patients underwent early fracture fixation, and the remainder underwent delayed fixation. No differences in the Short Form-36 (p = 0.68) or WOMAC (p = 0.69) scores were seen between the early and delayed fixation groups. Radiographic evidence of avascular necrosis developed in six patients treated with delayed fixation, one of whom had had an undisplaced fracture preoperatively, and in no patient treated with early fixation. The difference in the rates of avascular necrosis was significant (p = 0.03).Conclusions: Although delayed surgical treatment of subcapital hip fractures was associated with a higher rate of avascular necrosis, this complication did not significantly affect functional outcome. Longer follow-up is required to assess the effect of avascular necrosis on the development of arthritis and on long-term patient function. Although the results could be biased because patients were not randomly assigned to delayed or early fixation, the data suggest that urgent reduction and fracture fixation within twelve hours after a displaced subcapital hip fracture in high-demand patients may be associated with a reduced rate of radiographic signs of avascular necrosis.
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