2016-2019年秘鲁利马一家国家参考医院主动脉瓣置换术随访

Carlos Figueroa-Alfaro, Herbert Freyre-Ríos, Ciro Barrantes-Alarcón
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引用次数: 2

摘要

目的:探讨主动脉瓣置换术患者的围手术期特点;以及并发症,死亡率,随访和生存率。材料与方法:对2016 - 2019年手术患者进行回顾性研究。确定术前、术中和术后的特征,并进行临床和超声心动图随访。采用学生t检验比较均值。采用Kaplan-Meier法分析总生存期和无心血管事件生存期。结果:纳入患者110例(男性59.1%),平均年龄65.2±11.3岁,以动脉高血压为主(47.3%)。最常见的病因是退行性变性(47.3%)。机械假体植入率为59.1%。术后中位机械通气时间为8小时,平均ICU住院时间为5.8±6.7天。最常见的并发症是肺不张(21.8%)、心房颤动(19.1%)、低输出综合征、肺炎和急性肾损伤(各7.3%)。住院死亡率5.5%(心源性休克是常见原因)。随访1年,NYHA II-III功能等级(术前)改善至NYHA I-II功能等级(p <0.001),假体功能障碍发生率为13.3%(主要是由于瓣旁渗漏)。1年、3年和5年的总生存率分别为88、2±3、1、83.4±3.6%和74.3±5.0%。结论:主动脉瓣置换术在我们的环境中意味着生活质量的改善,具有良好的功能结果,并发症发生率,发病率和死亡率与世界文献相当。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Follow-up of the aortic valve replacement surgery in a national reference hospital in Lima, Peru, period 2016-2019
Objective: To describe the perioperative characteristics of patients undergoing aortic valve replacement; as well as complications, mortality, follow-up and survival. Materials and methods: A retrospective study of patients operated between 2016 and 2019 was carried out. Pre, intra, and postoperative characteristics were determined, as well as clinical and echocardiographic follow-up. Student's t test was used to compare means. Overall survival and cardiovascular event-free survival were analyzed using the Kaplan-Meier method. Results:110 patients were included (59.1% male), the mean age was 65.2 ± 11.3 years, the majority with arterial hypertension (47.3%). The most frequent etiology was degenerative (47.3%). A mechanical prosthesis was implanted in 59.1%. In the postoperative period, a median mechanical ventilation time of 8 hours was observed, with an average stay in the ICU of 5.8 ± 6.7 days. The most frequent complications were atelectasis (21.8%), atrial fibrillation (19.1%), low output syndrome, pneumonia, and acute kidney injury (7.3% each). Hospital mortality was 5.5% (cardiogenic shock as the frequent cause). During follow-up at one year, there was an improvement from NYHA II-III functional class (pre-surgical) to NYHA I-II (p <0.001), prosthesis dysfunction was found in 13.3% (the majority due to paravalvular leak). Overall survival at 1, 3, and 5 years was 88,2 ± 3,1, 83.4 ± 3.6% y 74.3 ± 5.0%, respectively. Conclusions: Aortic valve replacement surgery in our setting implies an improvement in quality of life with good functional results, complication rate, and morbidity and mortality comparable with the world literature.
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
46
审稿时长
12 weeks
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