{"title":"一种集成电化学生物传感器阵列的低噪声读出电路","authors":"Jichun Zhang, N. Trombly, A. Mason","doi":"10.1109/ICSENS.2004.1426093","DOIUrl":null,"url":null,"abstract":"This paper presents a low noise electrochemical interface circuit that is tuned to the needs of protein-based biosensor arrays and compatible with the formation of fully integrated biochemical microsystems. The circuit includes an integrated potentiostat and highly sensitive amperometric readout amplifier. It achieves good noise performance while supporting biosensor output currents from 10 pA to 10 /spl mu/A to suit a wide range of sensitivities and electrode areas. Implemented in 0.5 /spl mu/m CMOS process, it is compatible with a post-CMOS process to realize an integrated biosensor array.","PeriodicalId":20476,"journal":{"name":"Proceedings of IEEE Sensors, 2004.","volume":"8 1","pages":"36-39 vol.1"},"PeriodicalIF":0.0000,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"47","resultStr":"{\"title\":\"A low noise readout circuit for integrated electrochemical biosensor arrays\",\"authors\":\"Jichun Zhang, N. Trombly, A. Mason\",\"doi\":\"10.1109/ICSENS.2004.1426093\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper presents a low noise electrochemical interface circuit that is tuned to the needs of protein-based biosensor arrays and compatible with the formation of fully integrated biochemical microsystems. The circuit includes an integrated potentiostat and highly sensitive amperometric readout amplifier. It achieves good noise performance while supporting biosensor output currents from 10 pA to 10 /spl mu/A to suit a wide range of sensitivities and electrode areas. Implemented in 0.5 /spl mu/m CMOS process, it is compatible with a post-CMOS process to realize an integrated biosensor array.\",\"PeriodicalId\":20476,\"journal\":{\"name\":\"Proceedings of IEEE Sensors, 2004.\",\"volume\":\"8 1\",\"pages\":\"36-39 vol.1\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"47\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of IEEE Sensors, 2004.\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICSENS.2004.1426093\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of IEEE Sensors, 2004.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICSENS.2004.1426093","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A low noise readout circuit for integrated electrochemical biosensor arrays
This paper presents a low noise electrochemical interface circuit that is tuned to the needs of protein-based biosensor arrays and compatible with the formation of fully integrated biochemical microsystems. The circuit includes an integrated potentiostat and highly sensitive amperometric readout amplifier. It achieves good noise performance while supporting biosensor output currents from 10 pA to 10 /spl mu/A to suit a wide range of sensitivities and electrode areas. Implemented in 0.5 /spl mu/m CMOS process, it is compatible with a post-CMOS process to realize an integrated biosensor array.
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