S. Emre, Cigdem Moroglu, T. Yıldırmak, F. Şimşek, Çiğdem Arabacı, O. Ozkaya, N. Turgut, Merve Irmak
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引用次数: 2
摘要
耐药革兰氏阴性菌引起的感染越来越频繁。粘菌素用于治疗这些感染，但已经出现了耐粘菌素细菌和泛耐细菌。这种情况被认为在不久的将来会成为一个重要的健康问题。对于泛耐药细菌引起的感染，使用了各种联合疗法。双碳青霉烯方案，含或不含粘菌素，用于此目的。在本报告中，我们报告了两例不同的泛耐药肺炎克雷伯菌感染，第一例发生在坏死的皮肤病变，第二例发生在尿路感染治疗期间中心静脉导管相关菌血症，使用双碳青霉烯类药物治疗，其中一个与粘菌素一起治疗。Klimik Dergisi 2018;31(2): 169 - 72。
Combination Antibiotic Therapy in Pan-Resistant Klebsiella pneumoniae Infection: A Report of Two Cases
Infections caused by resistant Gram-negative bacteria are seen in increasing frequency. Colistin is used in the treatment of these infections but colistin-resistant bacteria and panresistant bacteria have emerged. This situation is thought to become an important health problem in the near future. Various combination therapies are used in the infections caused by pan-resistant bacteria. Double-carbapenem regimen, with or without colistin, is used for this purpose. In this report, we present two different cases of pan-resistant Klebsiella pneumoniae infection, first one developing on a necrotic skin lesion, and second one occurring as central venous catheterrelated bacteremia during the treatment of a urinary tract infection, treated with double carbapenems, one of them together with colistin. Klimik Dergisi 2018; 31(2): 169-72.
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