三级医院非血液学恶性患者的贫血模式:一项横断面研究

Mahbub Mayukh Rishad, Miftahul Jannat, Nur mohammad Rakib, Tania Sultana, Ishrat Binte Reza, Nawsabah Noor, Zafia Afrin, Monjurrahman, K. A. Azad
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摘要

背景:贫血是癌症患者的常见并发症,与生活质量下降和预后不良有关。考虑到发展中国家关于非血液病癌症患者贫血的数据缺乏,本研究旨在评估孟加拉国一家三级医院收治的非血液病癌症患者的贫血模式。方法:对2017年9月1日至2017年12月1日在印度医学院附属医院接受治疗的56例成人非血液学癌贫血患者进行横断面研究。在获得书面知情同意后,对每位患者进行详细的病史、临床检查和彻底的调查。本研究中的所有方法都是按照1975年赫尔辛基宣言的伦理准则进行的。数据以单独的病例记录表记录,并使用IBM SPSS version 26进行分析。结果:大多数研究参与者为男性(62.5%),年龄>50岁(64.3%),来自农村(60.7%)。转移影响了50%的研究参与者,结直肠癌(17.9%)是最常见的非血液学癌症类型。大多数患者有中度至重度(73.2%)、低色性(62.5%)和小细胞性(62.5%)贫血。与未患结直肠癌的患者相比,患有结直肠癌的患者更有可能患上严重贫血(p=0.001)。在有转移的患者中,血红蛋白低于10 g/dL的可能性是无转移患者的11.27倍(COR = 11.27;95% ci 2.23-56.86)。结论:重度贫血非血液病患者血红蛋白<10 g/dL,伴有小细胞增多和低色素血症。孟加拉国J医学2023;34 (3): 192 - 198
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pattern of Anaemia among Non-haematological Malignant Patients in a Tertiary Care Hospital: A Cross-sectional Study
Background: Anaemia is a frequent complication in cancer patients and has been linked to a reduction in quality of life as well as a poor prognosis. Considering the paucity of dataregarding anaemia in non-haematological carcinoma in developing countries, this studyaimed to evaluate the pattern of anaemia in non-haematological carcinoma patients admitted in a tertiary care hospital of Bangladesh. Methods: This cross-sectional study was conducted over 56 adult anaemic patients of nonhaematological carcinoma inDhaka Medical College Hospital, from 1st of September 2017 to 1stdecember 2017.After getting written informed consent, a detailed history, clinical examination and thorough investigation were carried out in each patient. All the methods in the present study were carried out following the ethical guidelines of the 1975 Declaration of Helsinki.Data were recorded in separated case record form and analyzed by IBM SPSS version 26. Results: The majority of the study participants were male (62.5%), aged >50 years (64.3%), and from rural areas (60.7%). Metastasis affected 50% of the research participants, and colorectal carcinoma (17.9%) was the most common type of non-haematological carcinoma. The majority of patients had moderate to severe (73.2%), hypochromic (62.5%), and microcytic (62.5%) anemia. In contrast to patients without colorectal cancer, those who had it were more likely to get severe anemia (p=0.001). In patients with metastasis, the likelihood of having hemoglobin below 10 g/dL was 11.27 times higher than in patients without metastasis (COR = 11.27; 95% CI 2.23-56.86). Conclusion: Maximum anaemic non-haematogical patients had haemoglobin <10 g/dL with microcytosis and hypochromia. Bangladesh J Medicine 2023; 34(3): 192-198
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