利用虚拟现实挖掘人类基因组

Bram Stolk, Faizal Abdoelrahman, A. Koning, Paul Wielinga, Jean-Marc Neefs, Andrew P. Stubbs, A. Bondt, P. Leemans, P. Spek
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引用次数: 18

摘要

基因组数据的分析和多种生物数据来源的整合已成为生命科学研究的难题。通过DNA微阵列等自动化技术收集新数据的速度加剧了这一问题。我们开发了一个虚拟现实应用程序,用于可视化基因家族中的层次关系和可视化基因表达数据网络。将来自多个数据库的其他信息与这些可视化结合起来,可以帮助制药研究人员选择新药的靶基因或蛋白质。我们发现虚拟现实在基因组学领域的应用是成功的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mining the human genome using virtual reality
The analysis of genomic data and integration of diverse biological data sources has become increasingly difficult for researches in the life sciences. This problem is exacerbated by the speed with which new data is gathered through automated technology like DNA microarrays. We developed a virtual reality application for visualizing hierarchical relationships within a gene family and for visualizing networks of gene expression data. Integration of other information from multiple databases with these visualizations can aid pharmaceutical researchers in selecting target genes or proteins for new drugs. We found the application of virtual reality to the field of genomics to be successfull.
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